(Z)-3-{3-butoxy-4-[2-(3-fluoro-4-hydroxy-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate

Base Information

• Chemical Name: (Z)-3-{3-butoxy-4-[2-(3-fluoro-4-hydroxy-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate
• CAS No.: 1092167-03-7
• Molecular Formula: C₂₅H₃₁FO₆
• Molecular Weight: 446.516

Synonyms:(Z)-3-{3-butoxy-4-[2-(3-fluoro-4-hydroxy-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate

Chemical Property of (Z)-3-{3-butoxy-4-[2-(3-fluoro-4-hydroxy-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate

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Technology Process of (Z)-3-{3-butoxy-4-[2-(3-fluoro-4-hydroxy-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate

There total 1 articles about (Z)-3-{3-butoxy-4-[2-(3-fluoro-4-hydroxy-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(Z)-3-(3-butoxy-4-{2-[3-fluoro-4-(2-methoxy-ethoxymethoxy)-phenyl]-ethoxy}-phenyl)-2-ethoxy-ethyl acrylate (1092167-02-6) → (Z)-3-{3-butoxy-4-[2-(3-fluoro-4-hydroxy-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate (1092167-03-7)

Guidance literature:

With sulfuric acid; In tetrahydrofuran; methanol; at 20 ℃; for 15h;

Reference yield: 75.0%

(Z)-3-{3-butoxy-4-[2-(3-fluoro-4-hydroxy-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate (1092167-03-7) + ethyl iodide (75-03-6) → (Z)-3-{3-butoxy-4-[2-(4-ethoxy-3-fluoro-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate (1092167-04-8)

Guidance literature:

With potassium carbonate; In butanone; at 80 ℃; for 4h;

Reference yield: 72.0%

amyl iodide (628-17-1) + (Z)-3-{3-butoxy-4-[2-(3-fluoro-4-hydroxy-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate (1092167-03-7) → (Z)-3-{3-butoxy-4-[2-(3-fluoro-4-pentyloxy-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate (1092167-06-0)

Guidance literature:

With potassium carbonate; In butanone; at 80 ℃; for 7h;

upstream raw materials:

(Z)-3-(3-butoxy-4-{2-[3-fluoro-4-(2-methoxy-ethoxymethoxy)-phenyl]-ethoxy}-phenyl)-2-ethoxy-ethyl acrylate

Downstream raw materials:

(Z)-3-{3-butoxy-4-[2-(3-fluoro-4-butanesulfonyloxy-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate

(Z)-3-{3-butoxy-4-[2-(4-ethoxy-3-fluoro-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate

(Z)-3-{3-butoxy-4-[2-(3-fluoro-4-pentyloxy-phenyl)-ethoxy]-phenyl}-2-ethoxy-ethyl acrylate

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