Technology Process of (1,3-diphenyl-1H-pyrrol-2-yl)-phenylmethanone
There total 3 articles about (1,3-diphenyl-1H-pyrrol-2-yl)-phenylmethanone which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
water; triethylamine; copper(l) chloride;
In
N,N-dimethyl-formamide;
at 85 - 90 ℃;
for 2h;
Inert atmosphere;
DOI:10.1016/j.tetlet.2011.09.070
- Guidance literature:
-
Multi-step reaction with 3 steps
1: phosphorus tribromide / chloroform
2: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine
3: water; triethylamine; copper(l) chloride / N,N-dimethyl-formamide / 2 h / 85 - 90 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; water; phosphorus tribromide; triethylamine; copper(l) chloride;
In
chloroform; N,N-dimethyl-formamide;
2: Sonogashira coupling;
DOI:10.1016/j.tetlet.2011.09.070
- Guidance literature:
-
Multi-step reaction with 2 steps
1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; triethylamine
2: water; triethylamine; copper(l) chloride / N,N-dimethyl-formamide / 2 h / 85 - 90 °C / Inert atmosphere
With
bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; water; triethylamine; copper(l) chloride;
In
N,N-dimethyl-formamide;
1: Sonogashira coupling;
DOI:10.1016/j.tetlet.2011.09.070
