C₁₁H₁₀F₂O₃

Base Information

• Chemical Name: C₁₁H₁₀F₂O₃
• CAS No.: 1276040-50-6
• Molecular Formula: C₁₁H₁₀F₂O₃
• Molecular Weight: 228.195
• Mol file: 1276040-50-6.mol

Synonyms:C₁₁H₁₀F₂O₃

Chemical Property of C₁₁H₁₀F₂O₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of C₁₁H₁₀F₂O₃

There total 1 articles about C₁₁H₁₀F₂O₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methanol (67-56-1) + 2-(2,4,6-trifluorophenyl)acetonitrile (220227-80-5) + ethylene dibromide (106-93-4) → C11H10F2O3 (1276040-50-6)

Guidance literature:

2,4,6-trifluorobenzyl cyanide; ethylene dibromide; With tetrabutylammomium bromide; potassium hydroxide; In water; at 20 ℃; for 16h;

methanol; With sodium hydroxide; In water; at 100 ℃; for 2h;

With hydrogenchloride; In water; pH=~ 1;

Reference yield:

C11H10F2O3 (1276040-50-6) → C11H9F2N3O2

Guidance literature:

With diphenyl phosphoryl azide; triethylamine; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

C11H10F2O3 (1276040-50-6) → C10H11F2NO (1276040-51-7)

Guidance literature:

Multi-step reaction with 3 steps

1.1: diphenyl phosphoryl azide; triethylamine / dichloromethane / 2 h / 20 °C

2.1: 1,4-dioxane / 1 h / 100 °C

2.2: 2 h / 100 °C

3.1: hydrogen / 5%-palladium/activated carbon / ethanol / 4 h / 760.05 Torr

With diphenyl phosphoryl azide; hydrogen; triethylamine; 5%-palladium/activated carbon; In 1,4-dioxane; ethanol; dichloromethane;

upstream raw materials:

methanol

2-(2,4,6-trifluorophenyl)acetonitrile

ethylene dibromide

Downstream raw materials:

C₁₀H₁₁F₂NO

Refernces