Ethyl 3-(2,4-Dichlorophenyl)-3-hydroxypropanoate

Base Information

Chemical Name:Ethyl 3-(2,4-Dichlorophenyl)-3-hydroxypropanoate
CAS No.:62547-76-6
Molecular Formula:C₁₁H₁₂Cl₂O₃
Molecular Weight:263.12
Hs Code.:
DSSTox Substance ID:DTXSID001253478

Synonyms:62547-76-6;Ethyl 3-(2,4-Dichlorophenyl)-3-hydroxypropanoate;DTXSID001253478;MFCD16756874;AKOS011682716;SY348612;Ethyl 2,4-dichloro-beta-hydroxybenzenepropanoate

Suppliers and Price of Ethyl 3-(2,4-Dichlorophenyl)-3-hydroxypropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Ethyl 3-(2,4-Dichlorophenyl)-3-hydroxypropanoate

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:262.0163496
Heavy Atom Count:16
Complexity:235

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)CC(C1=C(C=C(C=C1)Cl)Cl)O

Technology Process of Ethyl 3-(2,4-Dichlorophenyl)-3-hydroxypropanoate

There total 2 articles about Ethyl 3-(2,4-Dichlorophenyl)-3-hydroxypropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 874-42-0
2,4-dichlorobenzaldeyhde

: 105-36-2
ethyl bromoacetate

: 62547-76-6
ethyl 3-(2,4-dichlorophenyl)-3-hydroxy propanoate

Guidance literature:: With hydrogenchloride; magnesium(II) perchlorate; ammonium chloride; zinc; dibenzoyl peroxide; Yield given. Multistep reaction; 1.) H₂O, room temperature, 15 min, 2.) 5 min;
DOI:10.1021/jo970827k

Reference yield:

: 874-42-0
2,4-dichlorobenzaldeyhde

: 141-78-6
ethyl acetate

: 62547-76-6
ethyl 3-(2,4-dichlorophenyl)-3-hydroxy propanoate

Guidance literature:: ethyl acetate; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

2,4-dichlorobenzaldeyhde; In tetrahydrofuran; hexane; at -78 ℃; for 1h;
DOI:10.1016/j.tet.2004.12.059

Reference yield:

: 4229-44-1
N-methylhydroxyamine hydrochloride

: 62547-76-6
ethyl 3-(2,4-dichlorophenyl)-3-hydroxy propanoate

: 3-(2,4-dichlorophenyl)-3-hydroxy-N-methylpropionylhydroxamic acid

Guidance literature:: N-methylhydroxyamine hydrochloride; With sodium methylate; In methanol; for 0.166667h;

ethyl 3-(2,4-dichlorophenyl)-3-hydroxy propanoate; In methanol;
DOI:10.1016/j.bmc.2016.07.052