N-4-methoxyphenylphosphoramidic dichloride

Base Information

• Chemical Name: N-4-methoxyphenylphosphoramidic dichloride
• CAS No.: 51250-37-4
• Molecular Formula: C₇H₈Cl₂NO₂P
• Molecular Weight: 240.026
• Mol file: 51250-37-4.mol

Synonyms:N-4-methoxyphenylphosphoramidic dichloride

Chemical Property of N-4-methoxyphenylphosphoramidic dichloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-4-methoxyphenylphosphoramidic dichloride

There total 1 articles about N-4-methoxyphenylphosphoramidic dichloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methoxy-aniline (104-94-9) → N-4-methoxyphenylphosphoramidic dichloride (51250-37-4)

Guidance literature:

With trichlorophosphate;

Reference yield: 70.0%

N-4-methoxyphenylphosphoramidic dichloride (51250-37-4) + propan-1-ol-3-amine (156-87-6) → (4-methoxy-phenyl)-(2-oxo-2λ5-[1,3,2]oxazaphosphinan-2-yl)-amine (64077-23-2)

Guidance literature:

With triethylamine; In tetrachloromethane; at 0 ℃; for 10h;

DOI:10.1007/s00044-011-9737-7

Reference yield: 70.0%

N-4-methoxyphenylphosphoramidic dichloride (51250-37-4) + naphthalene-1,8-diamine (479-27-6) → 2-(4-methoxyanilino)-1,3,2-naphthodiazaphosphorinane-2-oxide (1332643-63-6)

Guidance literature:

With triethylamine; Inert atmosphere;

DOI:10.1134/S0022476611020077

upstream raw materials:

4-methoxy-aniline

Downstream raw materials:

bis-aziridin-1-yl-phosphinic acid p-anisidide

[1,3-bis-(4-chloro-benzyl)-2-oxo-2λ⁵-[1,3,2]diazaphosphinan-2-yl]-(4-methoxy-phenyl)-amine

[1,3-bis-(4-methoxy-benzyl)-2-oxo-2λ⁵-[1,3,2]diazaphosphinan-2-yl]-(4-methoxy-phenyl)-amine

(4-methoxy-phenyl)-(2-oxo-2λ⁵-[1,3,2]diazaphosphinan-2-yl)-amine