[(2S)-1-(benzenesulfonyl)pyrrolidin-2-yl]methanol

Base Information

Chemical Name:[(2S)-1-(benzenesulfonyl)pyrrolidin-2-yl]methanol
CAS No.:122030-80-2
Molecular Formula:C₁₁H₁₅NO₃S
Molecular Weight:241.311
Hs Code.:
European Community (EC) Number:824-786-7
Nikkaji Number:J1.485.487H
Wikidata:Q76506840

Synonyms:[(2S)-1-(benzenesulfonyl)pyrrolidin-2-yl]methanol;122030-80-2;(S)-(1-(phenylsulfonyl)pyrrolidin-2-yl)methanol;starbld0023501;N-benzenesulfonyl prolinol;SCHEMBL17600734;VDRGQWKLTZSRAY-JTQLQIEISA-N;AKOS015605229;CS-0236755;G27793;EN300-1725841

Suppliers and Price of [(2S)-1-(benzenesulfonyl)pyrrolidin-2-yl]methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of [(2S)-1-(benzenesulfonyl)pyrrolidin-2-yl]methanol

Chemical Property:

XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:241.07726451
Heavy Atom Count:16
Complexity:317

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC(N(C1)S(=O)(=O)C2=CC=CC=C2)CO
Isomeric SMILES:C1C[C@H](N(C1)S(=O)(=O)C2=CC=CC=C2)CO

Technology Process of [(2S)-1-(benzenesulfonyl)pyrrolidin-2-yl]methanol

There total 2 articles about [(2S)-1-(benzenesulfonyl)pyrrolidin-2-yl]methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 98-09-9
benzenesulfonyl chloride

: 23356-96-9
(S)-1-Pyrrolidin-2-yl-methanol

: 122030-80-2
(S)-N-Benzenesulfonyl-2-hydroxymethylpyrrolidine

Guidance literature:: With triethylamine; In dichloromethane; for 2h; Ambient temperature;
DOI:10.1248/cpb.39.260

Reference yield: 65.0%

: 88425-46-1
N-benzenesulfonyl-L-proline

: 122030-80-2
(S)-N-Benzenesulfonyl-2-hydroxymethylpyrrolidine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 2h; Ambient temperature;

Reference yield:

: 122030-80-2
(S)-N-Benzenesulfonyl-2-hydroxymethylpyrrolidine

: 123-11-5
4-methoxy-benzaldehyde

: 134295-57-1,134295-58-2
(1'R,2S)-N--2-hydroxymethylpyrrolidine

: 134295-57-1
(1'S,2S)-N--2-hydroxymethylpyrrolidine

Guidance literature:: With n-butyllithium; Yield given. Multistep reaction. Yields of byproduct given. Title compound not separated from byproducts; 1.) THF, hexane, 0 deg C, 30 min, 2.) 0 deg C, 3 h;
DOI:10.1248/cpb.39.260