9H-Purin-6-amine, 9-(5-O-((aminocarbonyl)hydroxyphosphinyl)-beta-D-ribofuranosyl)-

Base Information

Chemical Name:9H-Purin-6-amine, 9-(5-O-((aminocarbonyl)hydroxyphosphinyl)-beta-D-ribofuranosyl)-
CAS No.:104532-12-9
Molecular Formula:C29H29 N5 O4
Molecular Weight:374.2466
Hs Code.:
DSSTox Substance ID:DTXSID00146533
Wikidata:Q83011362

Synonyms:104532-12-9;9H-Purin-6-amine, 9-(5-O-((aminocarbonyl)hydroxyphosphinyl)-beta-D-ribofuranosyl)-;DTXSID00146533;9H-Purin-6-amine, 9-[5-O-[(aminocarbonyl)hydroxyphosphinyl]-.beta.-D-ribofuranosyl]-;[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl]methoxy-carbamoyl-phosphinic acid

Suppliers and Price of 9H-Purin-6-amine, 9-(5-O-((aminocarbonyl)hydroxyphosphinyl)-beta-D-ribofuranosyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 9H-Purin-6-amine, 9-(5-O-((aminocarbonyl)hydroxyphosphinyl)-beta-D-ribofuranosyl)-

Chemical Property:

Boiling Point:803.4°Cat760mmHg
Flash Point:439.7°C
Density:2.3g/cm³
XLogP3:-3.8
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:11
Rotatable Bond Count:5
Exact Mass:374.07398384
Heavy Atom Count:25
Complexity:569

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=NC(=C2C(=N1)N(C=N2)C3C(C(C(O3)COP(=O)(C(=O)N)O)O)O)N
Isomeric SMILES:C1=NC(=C2C(=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COP(=O)(C(=O)N)O)O)O)N

Technology Process of 9H-Purin-6-amine, 9-(5-O-((aminocarbonyl)hydroxyphosphinyl)-beta-D-ribofuranosyl)-

There total 2 articles about 9H-Purin-6-amine, 9-(5-O-((aminocarbonyl)hydroxyphosphinyl)-beta-D-ribofuranosyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 104532-11-8
(R)-2-[(R)-1-(6-Amino-purin-9-yl)-2-oxo-ethoxy]-3-trityloxy-propionaldehyde

: 104532-12-9
5'-O-(triphenylmethyl)-2',3'-secoadenosine

Guidance literature:: With sodium tetrahydroborate; In ethanol; for 2h; Ambient temperature;
DOI:10.1021/jm00162a005

Reference yield:

: 18048-85-6
5'-O-(triphenylmethyl)adenosine

: 104532-12-9
5'-O-(triphenylmethyl)-2',3'-secoadenosine

Guidance literature:: Multi-step reaction with 2 steps

1: 9.9 g / sodium periodate / methanol; H₂O / 20 h / Ambient temperature

2: 87 percent / NaBH₄ / ethanol / 2 h / Ambient temperature

With sodium tetrahydroborate; sodium periodate; In methanol; ethanol; water;
DOI:10.1021/jm00162a005