(2S)-2-[[(2S)-2-azaniumyl-3-phenylpropanoyl]amino]-3-hydroxypropanoate

Base Information

Chemical Name:(2S)-2-[[(2S)-2-azaniumyl-3-phenylpropanoyl]amino]-3-hydroxypropanoate
CAS No.:16053-39-7
Molecular Formula:C12H16 N2 O4
Molecular Weight:252.27
Hs Code.:
Mol file:16053-39-7.mol

Synonyms:

Suppliers and Price of (2S)-2-[[(2S)-2-azaniumyl-3-phenylpropanoyl]amino]-3-hydroxypropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chem-Impex
H-Phe-Ser-OH ≥ 99% (TLC)
1G
$ 125.00

Chem-Impex
H-Phe-Ser-OH ≥ 99% (TLC)
250MG
$ 60.00

Chem-Impex
H-Phe-Ser-OH,95.5%(HPLC) 95.5%(HPLC)
5G
$ 660.80

AK Scientific
H-Phe-Ser-OH
250mg
$ 131.00

Total 15 raw suppliers

Chemical Property of (2S)-2-[[(2S)-2-azaniumyl-3-phenylpropanoyl]amino]-3-hydroxypropanoate

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:571.168°C at 760 mmHg
PKA:2.97±0.10(Predicted)
Flash Point:299.232°C
PSA：112.65000
Density:1.322g/cm³
LogP:0.20930
Storage Temp.:-15°C
XLogP3:-3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:252.11100700
Heavy Atom Count:18
Complexity:284

Purity/Quality:

99% ^*data from raw suppliers

H-Phe-Ser-OH ≥ 99% (TLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)CC(C(=O)NC(CO)C(=O)[O-])[NH3+]
Isomeric SMILES:C1=CC=C(C=C1)C[C@@H](C(=O)N[C@@H](CO)C(=O)[O-])[NH3+]

Technology Process of (2S)-2-[[(2S)-2-azaniumyl-3-phenylpropanoyl]amino]-3-hydroxypropanoate

There total 5 articles about (2S)-2-[[(2S)-2-azaniumyl-3-phenylpropanoyl]amino]-3-hydroxypropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 35661-40-6
N-Fmoc L-Phe

: 71989-33-8
Fmoc-Ser(tBu)-OH

: 16053-39-7
L-phenylalanyl-L-serine

Guidance literature:: Fmoc-Ser(tBu)-OH; With 1-methyl-1H-imidazole; diisopropyl-carbodiimide; at 20 ℃; for 2h; Green chemistry;

With piperidine; In N,N-dimethyl-formamide; for 0.133333h; Green chemistry;

N-Fmoc L-Phe; Further stages; Green chemistry;
DOI:10.1016/j.tetlet.2019.151058

Reference yield:

: 135575-89-2
N-benzyloxycarbonyl-L-phenylalanyl-L-serine benzyl ester

: 16053-39-7
L-phenylalanyl-L-serine

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; Yield given;

Reference yield:

: 1161-13-3
N-Cbz-L-Phe

: 16053-39-7
L-phenylalanyl-L-serine

Guidance literature:: Multi-step reaction with 2 steps

1: 43 percent / DCC, NEt₃ / CH₂Cl₂

2: H₂ / 10percent Pd-C / ethanol

With hydrogen; triethylamine; dicyclohexyl-carbodiimide; palladium on activated charcoal; In ethanol; dichloromethane;