S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-{(2-diethylamino)ethyl}sulfoximide

Base Information

• Chemical Name: S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-{(2-diethylamino)ethyl}sulfoximide
• CAS No.: 1147096-76-1
• Molecular Formula: C₂₅H₂₇Cl₂N₅O₃S
• Molecular Weight: 548.493
• Mol file: 1147096-76-1.mol

Synonyms:S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-{(2-diethylamino)ethyl}sulfoximide

Chemical Property of S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-{(2-diethylamino)ethyl}sulfoximide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-{(2-diethylamino)ethyl}sulfoximide

There total 5 articles about S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-{(2-diethylamino)ethyl}sulfoximide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C27H29Cl2N5O4S → S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-{(2-diethylamino)ethyl}sulfoximide (1147096-76-1)

Guidance literature:

With sulfuric acid; for 3h;

Reference yield:

2-(4-(N-benzyloxycarbonyl-2-methoxyethylsulfonimidoyl)benzamido)-5-chloro-N-(5-chloropyridin-2-yl)benzamide (1147096-70-5) → S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-{(2-diethylamino)ethyl}sulfoximide (1147096-76-1)

Guidance literature:

Multi-step reaction with 5 steps

1: boron tribromide / dichloromethane / 3 h / -70 - 30 °C / Inert atmosphere

2: pyridine / dichloromethane / 3 h / 5 - 30 °C / Inert atmosphere

3: carbon tetrabromide; triphenylphosphine / dichloromethane / 3 h / 25 - 30 °C

4: 0.5 h / 25 - 30 °C

5: sulfuric acid / 3 h

With pyridine; carbon tetrabromide; sulfuric acid; boron tribromide; triphenylphosphine; In dichloromethane;

Reference yield:

S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-(2-hydroxyethyl)-sulfoximide (1147096-26-1) → S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-{(2-diethylamino)ethyl}sulfoximide (1147096-76-1)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine / dichloromethane / 3 h / 5 - 30 °C / Inert atmosphere

2: carbon tetrabromide; triphenylphosphine / dichloromethane / 3 h / 25 - 30 °C

3: 0.5 h / 25 - 30 °C

4: sulfuric acid / 3 h

With pyridine; carbon tetrabromide; sulfuric acid; triphenylphosphine; In dichloromethane;

upstream raw materials:

2-(4-(N-benzyloxycarbonyl-2-methoxyethylsulfonimidoyl)benzamido)-5-chloro-N-(5-chloropyridin-2-yl)benzamide

S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-(2-hydroxyethyl)-sulfoximide

S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-(2-hydroxyethyl)-N-acetyl sulfoximide

S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-(2-bromoethyl)-N-acetyl sulfoximide