S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-(2-hydroxyethyl)-N-acetyl sulfoximide

Base Information

Chemical Name:S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-(2-hydroxyethyl)-N-acetyl sulfoximide
CAS No.:1147096-71-6
Molecular Formula:C₂₃H₂₀Cl₂N₄O₅S
Molecular Weight:535.408
Hs Code.:

Synonyms:S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-(2-hydroxyethyl)-N-acetyl sulfoximide

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Chemical Property of S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-(2-hydroxyethyl)-N-acetyl sulfoximide

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Technology Process of S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-(2-hydroxyethyl)-N-acetyl sulfoximide

There total 2 articles about S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-(2-hydroxyethyl)-N-acetyl sulfoximide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 17.0%

: 1147096-26-1
S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-(2-hydroxyethyl)-sulfoximide

: 75-36-5
acetyl chloride

: 1147096-71-6
S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-(2-hydroxyethyl)-N-acetyl sulfoximide

Guidance literature:: With pyridine; In dichloromethane; at 5 - 30 ℃; for 3h; Inert atmosphere;

Reference yield:

: 1147096-70-5
2-(4-(N-benzyloxycarbonyl-2-methoxyethylsulfonimidoyl)benzamido)-5-chloro-N-(5-chloropyridin-2-yl)benzamide

: 1147096-71-6
S-[4-(N-{2-[N-(5-chloro(2-pyridyl))carbamoyl]-4-chlorophenyl}carbamoyl)phenyl]-S-(2-hydroxyethyl)-N-acetyl sulfoximide

Guidance literature:: Multi-step reaction with 2 steps

1: boron tribromide / dichloromethane / 3 h / -70 - 30 °C / Inert atmosphere

2: pyridine / dichloromethane / 3 h / 5 - 30 °C / Inert atmosphere

With pyridine; boron tribromide; In dichloromethane;