3-Chloro-cinnamic acid

Base Information

Chemical Name:3-Chloro-cinnamic acid
CAS No.:1866-38-2
Molecular Formula:C9H7ClO2
Molecular Weight:182.606
Hs Code.:29163990
DSSTox Substance ID:DTXSID1075147
Mol file:1866-38-2.mol

Synonyms:3-CHLORO-CINNAMIC ACID;DTXSID1075147;3-(3-chlorophenyl) acrylic acid;AKOS025243289;AB00370;3-(3-chlorophenyl) prop-2-enoic acid;SY003741;SY112390;FT-0615482;FT-0679176

Suppliers and Price of 3-Chloro-cinnamic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-Chlorocinnamic acid
5g
$ 45.00

TCI Chemical
3-Chlorocinnamic Acid >98.0%(T)
25g
$ 54.00

SynQuest Laboratories
3-Chlorocinnamic acid 98%
25 g
$ 50.00

Frontier Specialty Chemicals
3-Chlorocinnamic acid
100g
$ 291.00

Frontier Specialty Chemicals
3-Chlorocinnamic acid
5g
$ 22.00

Frontier Specialty Chemicals
3-Chlorocinnamic acid
25g
$ 88.00

Crysdot
3-(3-Chlorophenyl)acrylicacid 98%
500g
$ 267.00

Chemenu
3-(3-Chlorophenyl)acrylicacid 95+%
500g
$ 252.00

Biosynth Carbosynth
3-Chlorocinnamic acid
500 g
$ 185.00

Biosynth Carbosynth
3-Chlorocinnamic acid
100 g
$ 57.50

Total 66 raw suppliers

Chemical Property of 3-Chloro-cinnamic acid

Chemical Property:

Appearance/Colour:white crystalline powder or crystals
Vapor Pressure:8.89E-05mmHg at 25°C
Melting Point:161-164 °C(lit.)
Boiling Point:326.2 °C at 760 mmHg
PKA:4.29(at 25℃)
Flash Point:151.1 °C
PSA：37.30000
Density:1.332 g/cm³
LogP:2.43780
Storage Temp.:Room temperature.
Solubility.:soluble in Methanol
XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:182.0134572
Heavy Atom Count:12
Complexity:189

Purity/Quality:

99% ^*data from raw suppliers

3-Chlorocinnamic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xn;Xi
Hazard Codes:Xi,Xn
Statements: 20/21/22-36/37/38
Safety Statements: 22-24/25-36-26-37

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)Cl)C=CC(=O)O

Technology Process of 3-Chloro-cinnamic acid

There total 33 articles about 3-Chloro-cinnamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 42175-03-1,79432-89-6,24583-84-4
methyl (E)-3-(3-chlorophenyl)prop-2-enoate

: 1866-38-2,14473-90-6
m-Chlorocinnamic acid

Guidance literature:: With lithium hydroxide monohydrate; In tetrahydrofuran; water; at 20 ℃; for 2h;
DOI:10.1021/acs.jmedchem.9b01835

Reference yield: 96.0%

: 141-82-2
malonic acid

: 587-04-2
m-Chlorobenzaldehyde

: 1866-38-2,14473-90-6
m-Chlorocinnamic acid

Guidance literature:: malonic acid; m-Chlorobenzaldehyde; With piperidine; pyridine; Reflux;

With hydrogenchloride; In water; optical yield given as %de; Cooling with ice;
DOI:10.1021/jo901833y

Reference yield: 95.0%

: 108-37-2
1-bromo-3-chlorobenzene

: 79-10-7
acrylic acid

: 1866-38-2,14473-90-6
m-Chlorocinnamic acid

Guidance literature:: With [CH₃PPh₃]₂[Pd₂Br₂Cl₄]; sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 140 ℃; for 0.5h;
DOI:10.1055/s-0032-1317963