(2r)-1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)propan-1-one

Base Information

Chemical Name:(2r)-1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)propan-1-one
CAS No.:4931-27-5
Molecular Formula:C7H7N3
Molecular Weight:133.1506
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80356310
Nikkaji Number:J15.737F
Wikidata:Q27194439
ChEMBL ID:CHEMBL3039482
Mol file:4931-27-5.mol

Synonyms:ANGOLENSIN (R);(2r)-1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)propan-1-one;4842-48-2;Spectrum_000679;SpecPlus_000140;Spectrum2_000394;Spectrum3_000697;Spectrum4_001404;Spectrum5_000168;BSPBio_002453;KBioGR_001788;KBioSS_001159;SPECTRUM100616;DivK1c_006236;SPBio_000607;CHEMBL3039482;SCHEMBL12998482;KBio1_001180;KBio2_001159;KBio2_003727;KBio2_006295;KBio3_001673;DTXSID80356310;CHEBI:113545;[R,(-)]-1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)-1-propanone;CCG-38665;SDCCGMLS-0066394.P001;NCGC00160149-01;NCGC00160149-02;BS-44301;SR-05000002521;SR-05000002521-1;BRD-K98281970-001-02-6;BRD-K98281970-001-03-4;Q27194439;(2R)-1-(2,4-dihydroxyphenyl)-2-(4-methoxyphenyl)-1-propanone

Suppliers and Price of (2r)-1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)propan-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Labseeker
5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 95
5g
$ 1833.00

Chemcia Scientific
5-Methyl-[1,2,4]triazolo[1,5-a]pyridine ＞97%
1 G
$ 325.00

American Custom Chemicals Corporation
5-METHYL-[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 95.00%
5MG
$ 498.92

Total 8 raw suppliers

Chemical Property of (2r)-1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)propan-1-one

Chemical Property:

PSA：30.19000
Density:1.24g/cm³
LogP:1.03770
XLogP3:3.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:272.10485899
Heavy Atom Count:20
Complexity:322

Purity/Quality:

97% ^*data from raw suppliers

5-METHYL[1,2,4]TRIAZOLO[1,5-A]PYRIDINE 95 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C1=CC=C(C=C1)OC)C(=O)C2=C(C=C(C=C2)O)O
Isomeric SMILES:C[C@H](C1=CC=C(C=C1)OC)C(=O)C2=C(C=C(C=C2)O)O

Technology Process of (2r)-1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)propan-1-one

There total 4 articles about (2r)-1-(2,4-Dihydroxyphenyl)-2-(4-methoxyphenyl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: N-(6-methylpyrid-2-yl)formamidoxime

: 4931-27-5
5-methyl[1,2,4]triazolo[1,5-a]pyridine

Guidance literature:: With trifluoroacetic anhydride; In tetrahydrofuran; at 20 ℃;
DOI:10.1002/ejoc.200500247

Reference yield:

: 1824-81-3
2-Amino-6-methylpyridine

: 4931-27-5
5-methyl[1,2,4]triazolo[1,5-a]pyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: propan-2-ol / Heating

1.2: 81 percent / hydroxylamine hydrochloride / propan-2-ol / 50 °C

2.1: 91 percent / trifluoroacetic anhydride / tetrahydrofuran / 20 °C

With trifluoroacetic anhydride; In tetrahydrofuran; isopropyl alcohol;
DOI:10.1002/ejoc.200500247

Reference yield:

: 274-85-1
s-triazolo(1,5-a)pyridine

: 74-88-4
methyl iodide

: 4931-27-5
5-methyl[1,2,4]triazolo[1,5-a]pyridine

Guidance literature:: With n-butyllithium; Yield given. Multistep reaction; 1.) THF, hexane, -78 deg C, 30 min, 2a.) -78 deg C, 5 min, 2b.) -78 deg C to RT;
DOI:10.1021/jo00046a045