3-(Dimethylamino)-N,N-dimethylpropionamide

Base Information

• Chemical Name: 3-(Dimethylamino)-N,N-dimethylpropionamide
• CAS No.: 17268-47-2
• Molecular Formula: C7H16 N2 O
• Molecular Weight: 144.217
• Hs Code.: 2924199090
• European Community (EC) Number: 241-304-5
• DSSTox Substance ID: DTXSID8066181
• Nikkaji Number: J35.362K
• Wikidata: Q81992760
• Mol file: 17268-47-2.mol

Synonyms:3-(Dimethylamino)-N,N-dimethylpropionamide;17268-47-2;3-(dimethylamino)-N,N-dimethylpropanamide;Propanamide, 3-(dimethylamino)-N,N-dimethyl-;BRN 1702593;3-Dimethylamino-N,N-dimethylpropionamide;EINECS 241-304-5;AI3-61372;Propionamide, 3-dimethylamino-N,N-dimethyl-;4-04-00-02532 (Beilstein Handbook Reference);SCHEMBL476756;DTXSID8066181;AKOS006230558;LS-124158;F89653;Propionamide, 3-(dimethylamino)-N,N-dimethyl-;EN300-6944422

Chemical Property of 3-(Dimethylamino)-N,N-dimethylpropionamide

Chemical Property:

• Vapor Pressure: 0.276mmHg at 25°C
• Refractive Index: 1.4585 (23℃)
• Boiling Point: 203.6 °C at 760 mmHg
• Flash Point: 69.7 °C
• PSA: 23.55000
• Density: 0.926 g/cm³
• LogP: 0.02630
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 144.126263138
• Heavy Atom Count: 10
• Complexity: 110

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCC(=O)N(C)C

Technology Process of 3-(Dimethylamino)-N,N-dimethylpropionamide

There total 10 articles about 3-(Dimethylamino)-N,N-dimethylpropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.84%

3-dimethylaminopropionic acid (6300-04-5) + dimethyl amine (124-40-3) → 3-(N,N-dimethylamino)-N',N'-dimethylpropionamide (17268-47-2)

Guidance literature:

alumina N₆₁₁N; at 150 ℃; under 2250.23 Torr; Product distribution / selectivity; Inert atmosphere;

Reference yield: 83.0%

N,N-Dimethylacrylamide (2680-03-7,68761-83-1) + dimethyl amine (124-40-3) → 3-(N,N-dimethylamino)-N',N'-dimethylpropionamide (17268-47-2)

Guidance literature:

With 2,6-di-tert-butyl-4-methyl-phenol; In water; at 85 ℃; for 2.5h;

DOI:10.1021/jo00232a038

Reference yield: 76.0%

→ 3-(N,N-dimethylamino)-N',N'-dimethylpropionamide (17268-47-2)

Guidance literature:

upstream raw materials:

dimethyl amine

ethyl acrylate

2-chloropropionyl chloride

N,N-Dimethylacrylamide

Downstream raw materials:

N,N-Dimethylacrylamide

N,N,N'N'-tetramethyl-1,3-propanediamine

β-methoxy-N,N-dimethylpropionic acid amide