Tagorizine

Base Information

Chemical Name:Tagorizine
CAS No.:118420-47-6
Molecular Formula:C30H36 N4 O
Molecular Weight:468.633
Hs Code.:
UNII:668QM8QJFS
Nikkaji Number:J524.240A,J596.950F
Wikidata:Q27263974
NCI Thesaurus Code:C73066
ChEMBL ID:CHEMBL154139
Mol file:118420-47-6.mol

Synonyms:AL 3264;AL-3264;N-(4-(4-(diphenylmethyl)-1-piperazinyl)butyl)-3-(6-methyl-3-pyridyl)acrylamide

Suppliers and Price of Tagorizine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
TAGORIZINE 95.00%
5MG
$ 503.94

Total 0 raw suppliers

Chemical Property of Tagorizine

Chemical Property:

Vapor Pressure:4.57E-17mmHg at 25°C
Boiling Point:655.6°C at 760 mmHg
Flash Point:350.3°C
PSA：51.96000
Density:1.119g/cm³
LogP:5.42290
XLogP3:4.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:10
Exact Mass:468.28891178
Heavy Atom Count:35
Complexity:614

Purity/Quality:: TAGORIZINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=C(C=C1)C=CC(=O)NCCCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4
Isomeric SMILES:CC1=NC=C(C=C1)/C=C/C(=O)NCCCCN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of Tagorizine

There total 6 articles about Tagorizine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

aqueous potassium carbonate: aqueous potassium carbonate

: 3282-30-2
pivaloyl chloride

: 101620-10-4
4-(4-diphenyl-methyl-1-piperazinyl)butylamine

: 117830-17-8
3-(6-methyl-pyridin-3-yl)-acrylic acid

: 118420-47-6
N-[3-(6-methyl-pyridin-3-yl)acryloyl]-4-(4-diphenylmethyl-1-piperazinyl)butylamine

Guidance literature:: With triethylamine; In tetrahydrofuran;

Reference yield:

: 53014-84-9
2-methyl-5-formylpyridine

: 118420-47-6
N-[3-(6-methyl-pyridin-3-yl)acryloyl]-4-(4-diphenylmethyl-1-piperazinyl)butylamine

Guidance literature:: Multi-step reaction with 3 steps

1: 77 percent / piperidine / pyridine / 100 °C

2: triethylamine / tetrahydrofuran / 0.5 h / -5 °C

3: tetrahydrofuran / 1.) -10 to -5 deg C, 30 min, 2.) r.t., overnight

With piperidine; triethylamine; In tetrahydrofuran; pyridine;
DOI:10.1021/jm00123a012

Reference yield:

: 34107-46-5
6-methyl-3-pyridinemethanol

: 118420-47-6
N-[3-(6-methyl-pyridin-3-yl)acryloyl]-4-(4-diphenylmethyl-1-piperazinyl)butylamine

Guidance literature:: Multi-step reaction with 4 steps

1: 57 percent / Pb(OAc)4 / toluene / 2.5 h / Heating

2: 77 percent / piperidine / pyridine / 100 °C

3: triethylamine / tetrahydrofuran / 0.5 h / -5 °C

4: tetrahydrofuran / 1.) -10 to -5 deg C, 30 min, 2.) r.t., overnight

With piperidine; lead(IV) acetate; triethylamine; In tetrahydrofuran; pyridine; toluene;
DOI:10.1021/jm00123a012