2,2,2,3'-Tetrafluoroacetophenone

Base Information

Chemical Name:2,2,2,3'-Tetrafluoroacetophenone
CAS No.:708-64-5
Molecular Formula:C8H4F4O
Molecular Weight:192.113
Hs Code.:29147000
European Community (EC) Number:211-903-6
NSC Number:158170
DSSTox Substance ID:DTXSID4061042
Nikkaji Number:J193.076A
Wikidata:Q72505044
Mol file:708-64-5.mol

Synonyms:708-64-5;2,2,2,3'-Tetrafluoroacetophenone;2,2,2-trifluoro-1-(3-fluorophenyl)ethanone;2,2,2-Trifluoro-1-(3-fluorophenyl)ethan-1-one;m-Fluorotrifluoroacetophenone;Acetophenone, 2,2,2,3'-tetrafluoro-;Ethanone, 2,2,2-trifluoro-1-(3-fluorophenyl)-;2,2,2,3'-Trtrafluoroacetophenone;EINECS 211-903-6;MFCD00039236;NSC 158170;m,alpha,alpha,alpha-Tetrafluoroacetophenone;NSC158170;SCHEMBL1273634;a,a,a,3-Tetrafluoroacetophenone;DTXSID4061042;PHORBOL12,13-DIBENZOATE;Acetophenone,2,2,3'-tetrafluoro-;AMY18968;CK2590;Acetophenone, 2,2,2,3'-tetrafluoro;AKOS009157033;NSC-158170;PS-8346;m,.alpha.,.alpha.-Tetrafluoroacetophenone;2,2,2,3'-Tetrafluoroacetophenone, 99%;alpha,alpha,alpha,3'-Tetrafluoroacetophenone;CS-0042634;FT-0609020;Ethanone,2,2-trifluoro-1-(3-fluorophenyl)-;2,2,2-trifluoro-1-( 3-fluorophenyl)ethanone;m-Fluoro-.alpha.,.alpha.-trifluoroacetophenone;EN300-1932845

Suppliers and Price of 2,2,2,3'-Tetrafluoroacetophenone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2,2,2,3'-Tetrafluoroacetophenone 99%
5 g
$ 65.00

SynQuest Laboratories
2,2,2,3'-Tetrafluoroacetophenone 99%
1 g
$ 25.00

SynQuest Laboratories
2,2,2,3'-Tetrafluoroacetophenone 99%
25 g
$ 275.00

Sigma-Aldrich
2,2,2,3′-Tetrafluoroacetophenone 99%
10g
$ 209.00

Rieke Metals
2,2,2,3'-tetrafluoroacetophenone 97%
5g
$ 1059.00

Rieke Metals
2,2,2,3'-tetrafluoroacetophenone 97%
2g
$ 516.00

Rieke Metals
2,2,2,3'-tetrafluoroacetophenone 97%
1g
$ 340.00

Oakwood
2,2,2,3'-tetrafluoroacetophenone 95%
250mg
$ 19.00

Matrix Scientific
2,2,2,3'-Tetrafluoroacetophenone 99%
5g
$ 77.00

Matrix Scientific
2,2,2,3'-Tetrafluoroacetophenone 99%
1g
$ 26.00

Total 40 raw suppliers

Chemical Property of 2,2,2,3'-Tetrafluoroacetophenone

Chemical Property:

Refractive Index:n20/D 1.444(lit.)
Boiling Point:172.3 °C at 760 mmHg
Flash Point:62.2 °C
PSA：17.07000
Density:1.357 g/cm³
LogP:2.57070
Storage Temp.:2-8°C
XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:192.01982740
Heavy Atom Count:13
Complexity:199

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,2,2,3'-Tetrafluoroacetophenone 99% ^*data from reagent suppliers

Safty Information:

Pictogram(s): F,Xi
Hazard Codes:F,Xi
Statements: 11-36/37/38
Safety Statements: 16-26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC(=C1)F)C(=O)C(F)(F)F

Technology Process of 2,2,2,3'-Tetrafluoroacetophenone

There total 8 articles about 2,2,2,3'-Tetrafluoroacetophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 383-63-1
ethyl trifluoroacetate,

: 1073-06-9
3-fluorobromobenzene

: 708-64-5
2,2,2,3'-tetrafluoroacetophenone

Guidance literature:: 3-fluorobromobenzene; With magnesium; In diethyl ether; Inert atmosphere;

ethyl trifluoroacetate,; In diethyl ether; at -78 - -50 ℃; for 3.5h; Inert atmosphere;
DOI:10.1021/acs.orglett.6b03743

Reference yield:

: 75-46-7
trifluoromethan

: 451-02-5
ethyl 3-fluorobenzoate

: 708-64-5
2,2,2,3'-tetrafluoroacetophenone

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; sodium; diisopropylamine; isoprene; In n-heptane; at -60 ℃; for 2h; Inert atmosphere;
DOI:10.1002/ejoc.201900250