Technology Process of Carbonic acid ethyl ester 5-(3-hydroxy-propyl)-2-oxo-4-phenyl-2,5-dihydro-furan-3-yl ester
There total 8 articles about Carbonic acid ethyl ester 5-(3-hydroxy-propyl)-2-oxo-4-phenyl-2,5-dihydro-furan-3-yl ester which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 97 percent / NaH / tetrahydrofuran / Ambient temperature
2: 99 percent / MCPBA / CH2Cl2 / Ambient temperature
3: EtONa / ethanol / Heating
4: 80 percent / aq. NaOH / Heating
5: 77 percent / Me2NH, AcONa / acetic acid / 100 °C
6: 42 percent / OsO4,NaIO4 / dioxane / Ambient temperature
7: 96 percent / H2 / Pd-black / ethanol
8: 92 percent / Et3N / tetrahydrofuran / 0 °C
With
sodium periodate; osmium(VIII) oxide; hydrogen; sodium ethanolate; sodium acetate; sodium hydride; dimethyl amine; triethylamine; 3-chloro-benzenecarboperoxoic acid;
palladium;
In
tetrahydrofuran; 1,4-dioxane; sodium hydroxide; ethanol; dichloromethane; acetic acid;
DOI:10.1016/S0040-4039(00)84436-6
- Guidance literature:
-
Multi-step reaction with 7 steps
1: 99 percent / MCPBA / CH2Cl2 / Ambient temperature
2: EtONa / ethanol / Heating
3: 80 percent / aq. NaOH / Heating
4: 77 percent / Me2NH, AcONa / acetic acid / 100 °C
5: 42 percent / OsO4,NaIO4 / dioxane / Ambient temperature
6: 96 percent / H2 / Pd-black / ethanol
7: 92 percent / Et3N / tetrahydrofuran / 0 °C
With
sodium periodate; osmium(VIII) oxide; hydrogen; sodium ethanolate; sodium acetate; dimethyl amine; triethylamine; 3-chloro-benzenecarboperoxoic acid;
palladium;
In
tetrahydrofuran; 1,4-dioxane; sodium hydroxide; ethanol; dichloromethane; acetic acid;
DOI:10.1016/S0040-4039(00)84436-6