N-Methyldodecylamine

Base Information

• Chemical Name: N-Methyldodecylamine
• CAS No.: 7311-30-0
• Molecular Formula: C13H29 N
• Molecular Weight: 199.38
• Hs Code.: 2921199090
• European Community (EC) Number: 230-771-0
• NSC Number: 165791
• UNII: 88NN43I94S
• DSSTox Substance ID: DTXSID90223387
• Nikkaji Number: J45.998D
• Wikidata: Q27269943
• ChEMBL ID: CHEMBL4763115
• Mol file: 7311-30-0.mol

Synonyms:N-methyldodecylamine;N-methyldodecylamine hydrochloride

Chemical Property of N-Methyldodecylamine

Chemical Property:

• Appearance/Colour: colourless liquid
• Melting Point: 18-19℃
• Refractive Index: 1.4395
• Boiling Point: 90 - 92 C at 0.9 mm Hg
• PKA: 10.78±0.10(Predicted)
• Flash Point: >110°C
• PSA: 12.03000
• Density: 0,795 g/cm3
• LogP: 4.51760
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Water Solubility.: Not miscible in water.
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 11
• Exact Mass: 199.229999929
• Heavy Atom Count: 14
• Complexity: 91.2

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Methyldodecylamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 1739959
• Hazard Codes: C
• Statements: 34
• Safety Statements: 26-36/37/39-45-27

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCNC
• Uses: N-Methyldodecylamine may be used for the preparation of N,N,N,N,N,N-trimethyldodecylammonium bromide.

Technology Process of N-Methyldodecylamine

There total 45 articles about N-Methyldodecylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + n-Dodecylamine (124-22-1) → N-methyldodecylamine (7311-30-0)

Guidance literature:

With butyl triphenylphosphonium tetraborate; at 20 ℃; for 0.183333h;

Reference yield: 94.0%

1-dodecylbromide (143-15-7) + methylamine (74-89-5) → N-methyldodecylamine (7311-30-0)

Guidance literature:

In ethanol; for 72h; Ambient temperature;

DOI:10.1007/BF00769386

Reference yield: 86.0%

methylamine hydrochloride (593-51-1) + 1-dodecylbromide (143-15-7) → N-methyldodecylamine (7311-30-0)

Guidance literature:

With tetra-(n-butyl)ammonium iodide; caesium carbonate; In N,N-dimethyl-formamide; at 23 ℃; for 5h;

DOI:10.1021/jo010643c

upstream raw materials:

lauric acid methylamide

tridecanoic acid[2,6-diethyl-2,3,6-trimethyl-1-(1-phenyl-ethoxy)-piperidin-4-yl]-amide

N-benzyl-N-methyldodecan-1-amine

1-dodecylbromide

Downstream raw materials:

N-lauryl-sarcosine

N-methyldidodecylamine

N-benzyl-N-methyldodecan-1-amine

C₂₀H₃₃N₃O₂

Refernces

• 1、 Biswas, Nandita,Srimani, Dipankar. "Ru-Catalyzed Selective Catalytic Methylation and Methylenation Reaction Employing Methanol as the C1 Source". . p. 10544 - 10554. Retrieved 2021/07/31.
• 2、 Yao, Wubing,Fang, Huaquan,He, Qiaoxing,Peng, Dongjie,Liu, Guixia,Huang, Zheng. "A BEt3-Base catalyst for amide reduction with silane". . . Retrieved 2019/05/22.