O-ACETYL-L-TYROSINE

Base Information

• Chemical Name: O-ACETYL-L-TYROSINE
• CAS No.: 6636-22-2
• Molecular Formula: C11H13 N O4
• Molecular Weight: 223.229
• Hs Code.: 2922509090
• Mol file: 6636-22-2.mol

Synonyms:L-Tyrosine,acetate (ester) (9CI); Tyrosine, acetate (7CI); Tyrosine, acetate (ester), L-(8CI); NSC 16556; O-Acetyl-L-tyrosine; O-Acetyltyrosine

Chemical Property of O-ACETYL-L-TYROSINE

Chemical Property:

• Vapor Pressure: 1.21E-06mmHg at 25°C
• Boiling Point: 385.8°C at 760 mmHg
• Flash Point: 187.1°C
• PSA: 89.62000
• Density: 1.275g/cm³
• LogP: 1.26660
• Storage Temp.: Store at 0-5°C
• Solubility.: Aqueous Acid (Slightly, Sonicated), DMSO (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

O-Acetyl-L-tyrosine ^*data from reagent suppliers

Safty Information:

• Safety Statements: S22:Do not inhale dust.; S24/25:Avoid contact with skin and eyes.

MSDS Files:

SDS file from LookChem

Useful:

• Uses: O-Acetyl-L-tyrosine can be prepared as an anti-tumor agent.

Technology Process of O-ACETYL-L-TYROSINE

There total 8 articles about O-ACETYL-L-TYROSINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

L-tyrosine (60-18-4,18875-48-4,25619-78-7,30704-25-7) + acetyl chloride (75-36-5) → O-acetyl-L-tyrosine (6636-22-2,36534-47-1)

Guidance literature:

With perchloric acid; In ethyl acetate; for 5h; Heating;

DOI:10.1002/jps.2600741210

Reference yield:

C18H23NO7 → O-Acetyl-tyrosin (6636-22-2,36534-47-1)

Guidance literature:

With hydrogenchloride; In water; at 110 ℃; Microwave irradiation;

DOI:10.1021/acs.orglett.8b02791

Reference yield:

O-acetyl-N-benzyloxycarbonyl L-tyrosine (51514-13-7) → O-acetyl-L-tyrosine (6636-22-2,36534-47-1)

Guidance literature:

With palladium; acetic acid; Hydrogenation;

DOI:10.1021/ja01234a034

upstream raw materials:

O-acetyl-N-benzyloxycarbonyl L-tyrosine

L-tyrosine

acetic acid

acetyl chloride

Downstream raw materials:

O-acetyl-N-((E)-2-methyl-3-phenyl-acryloyl)-tyrosine

L-Tyr(OAc) NCA

N-(O-acetyl-N-cyclopentyloxycarbonyl-L-tyrosyl)-glycine methyl ester

N^α-t-butyloxycarbonyl-L-valyl-O-acetyl-L-tyrosine