4-Fluoro-2-methoxyphenol

Base Information

Chemical Name:4-Fluoro-2-methoxyphenol
CAS No.:450-93-1
Molecular Formula:C7H7FO2
Molecular Weight:142.13
Hs Code.:29095000
European Community (EC) Number:626-485-4
DSSTox Substance ID:DTXSID80196359
Nikkaji Number:J2.639.300K
Wikidata:Q72474153
Mol file:450-93-1.mol

Synonyms:4-fluoro-2-methoxyphenol;4-fluoroguaiacol

Suppliers and Price of 4-Fluoro-2-methoxyphenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-Fluoro-2-methoxyphenol
5g
$ 75.00

TCI Chemical
4-Fluoro-2-methoxyphenol >97.0%(GC)
5g
$ 84.00

TCI Chemical
4-Fluoro-2-methoxyphenol >97.0%(GC)
1g
$ 26.00

SynQuest Laboratories
4-Fluoro-2-methoxyphenol 98%
100 g
$ 312.00

SynQuest Laboratories
4-Fluoro-2-methoxyphenol 98%
25 g
$ 120.00

Sigma-Aldrich
4-Fluoro-2-methoxyphenol 97%
5g
$ 118.00

Oakwood
4-Fluoro-2-methoxyphenol 97%
1g
$ 14.00

Matrix Scientific
4-Fluoro-2-methoxyphenol
1g
$ 20.00

Matrix Scientific
4-Fluoro-2-methoxyphenol
5g
$ 92.00

Frontier Specialty Chemicals
4-Fluoro-2-methoxyphenol 98%
5g
$ 120.00

Total 57 raw suppliers

Chemical Property of 4-Fluoro-2-methoxyphenol

Chemical Property:

Appearance/Colour:Clear slightly yellow liquid
Refractive Index:n20/D 1.517(lit.)
Boiling Point:201.9 °C at 760 mmHg
PKA:9.98±0.18(Predicted)
Flash Point:101.4 °C
PSA：29.46000
Density:1.224 g/cm³
LogP:1.53990
Storage Temp.:Inert atmosphere,Room Temperature
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:142.04300762
Heavy Atom Count:10
Complexity:108

Purity/Quality:

99%, ^*data from raw suppliers

4-Fluoro-2-methoxyphenol ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi, T
Hazard Codes:Xi,T
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)F)O
Uses 4-Fluoro-2-methoxyphenol may be used in the synthesis of:4-halo-masked o-benzoquinones (MOBs)fluorinated masked o-benzoquinonepoly(4-fluoro-2-methoxyphenol)

Technology Process of 4-Fluoro-2-methoxyphenol

There total 4 articles about 4-Fluoro-2-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 450-89-5
1-chloro-4-fluoro-2-methoxybenzene

: 450-93-1
2-methoxy-4-fluorophenol

Guidance literature:: With copper acetylacetonate; N¹-(4-hydroxy-2,6-dimethylphenyl)-N²-(4-hydroxy-3,5-dimethylphenyl)oxalamide; water; In water; dimethyl sulfoxide; at 130 ℃; for 24h; Schlenk technique; Inert atmosphere;
DOI:10.1021/jacs.6b08114

Reference yield: 86.0%

: 107756-57-0
1-Fluoro-3-methoxy-4-[(2-propenyl)oxy]benzene

: 450-93-1
2-methoxy-4-fluorophenol

Guidance literature:: 1-Fluoro-3-methoxy-4-[(2-propenyl)oxy]benzene; With sec.-butyllithium; In diethyl ether; hexane; cyclohexane; at -78 ℃; for 2h; Inert atmosphere;

With methanol; In diethyl ether; hexane; cyclohexane; at -78 ℃; Inert atmosphere;
DOI:10.1055/s-2008-1077962

Reference yield: 71.0%

: 51788-80-8
1-(4-fluoro-2-methoxy-phenyl)-ethanone

: 450-93-1
2-methoxy-4-fluorophenol

Guidance literature:: 1-(4-fluoro-2-methoxy-phenyl)-ethanone; With 6,6'-di-tert-butyl-4,4'-thiodi-o-cresol; 3-chloro-benzenecarboperoxoic acid; In dichloromethane; Heating;

With sodium hydroxide; In ethanol; for 2h;
DOI:10.1021/jm0304010