1-Benzyloxy-2-ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-benzene

Base Information

• Chemical Name: 1-Benzyloxy-2-ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-benzene
• CAS No.: 222022-96-0
• Molecular Formula: C₂₄H₃₂O₂
• Molecular Weight: 352.517
• Mol file: 222022-96-0.mol

Synonyms:1-Benzyloxy-2-ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-benzene

Chemical Property of 1-Benzyloxy-2-ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-benzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-Benzyloxy-2-ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-benzene

There total 7 articles about 1-Benzyloxy-2-ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ethyl iodide (75-03-6) + (1'S)-2-benzyloxy-4-methyl-6-(1',2',2'-trimethylcyclopentyl)phenol (222022-94-8) → 1-Benzyloxy-2-ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-benzene (222022-96-0)

Guidance literature:

With benzyl tri-n-butylammonium bromide; caesium carbonate; In acetone;

DOI:10.1016/S0040-4039(98)02487-3

Reference yield:

benzyl bromide (100-39-0) → 1-Benzyloxy-2-ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-benzene (222022-96-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / K₂CO₃ / acetone / Ambient temperature

2: 85 percent / Cs₂CO₃, Bzl(n-Bu)3NBr / acetone

With benzyl tri-n-butylammonium bromide; potassium carbonate; caesium carbonate; In acetone;

DOI:10.1016/S0040-4039(98)02487-3

Reference yield:

(S)-5-methyl-3-(1,2,2-trimethylcyclopentyl)benzene-1,2-diol (86996-95-4) → 1-Benzyloxy-2-ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-benzene (222022-96-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 90 percent / K₂CO₃ / acetone / Ambient temperature

2: 85 percent / Cs₂CO₃, Bzl(n-Bu)3NBr / acetone

With benzyl tri-n-butylammonium bromide; potassium carbonate; caesium carbonate; In acetone;

DOI:10.1016/S0040-4039(98)02487-3

upstream raw materials:

ethyl iodide

(1'S)-2-benzyloxy-4-methyl-6-(1',2',2'-trimethylcyclopentyl)phenol

benzyl bromide

(S)-5-methyl-3-(1,2,2-trimethylcyclopentyl)benzene-1,2-diol

Downstream raw materials:

2-Ethoxy-5-methyl-3-((S)-1,2,2-trimethyl-cyclopentyl)-phenol