Chemical Property of 1,3,5-Triazine-2,4-diamine
Chemical Property:
- Vapor Pressure:3.32E-08mmHg at 25°C
- Melting Point:>300°C
- Refractive Index:1.716
- Boiling Point:447.6 °C at 760 mmHg
- PKA:4.24±0.10(Predicted)
- Flash Point:254.9 °C
- PSA：90.71000
- Density:1.508 g/cm3
- LogP:0.19840
- Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
- XLogP3:-0.7
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:5
- Rotatable Bond Count:0
- Exact Mass:111.05449518
- Heavy Atom Count:8
- Complexity:66.1
- Purity/Quality:
-
97% *data from raw suppliers
2,4-Diamino-1,3,5-triazine *data from reagent suppliers
Safty Information:
- Pictogram(s):
R36/37/38:Irritating to eyes, respiratory system and skin.;
- Hazard Codes:R36/37/38:Irritating to eyes, respiratory system and skin.;
- Statements:
36/37/38
- Safety Statements:
26-36/37/39
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1=NC(=NC(=N1)N)N
-
Uses
2,4-Diamino-1,3,5-triazine is a reactant or reagent that has numerous uses. A triazine-modified dendrimer G5-DAT66 was synthesized and used as a vector for osteosarcoma TRAIL gene therapy in vitro and in vivo. 2,4-Diamino-1,3,5-triazine was also used to synthesize water soluble copper(II)-dipeptide complexes which exhibited considerable in vitro cytotoxicity against four human carcinoma cell lines (HepG2, HeLa, A549 and U87). These water soluble DNA minor groove binding diamino-s-triazine copper based complexes are potential chemotherapeutic agents.
