N-(1,2-diphenylethyl)-n-propylamine

Base Information

• Chemical Name: N-(1,2-diphenylethyl)-n-propylamine
• CAS No.: 119486-00-9
• Molecular Formula: C₁₇H₂₁N
• Molecular Weight: 239.36
• Mol file: 119486-00-9.mol

Synonyms:N-(1,2-diphenylethyl)-n-propylamine

Chemical Property of N-(1,2-diphenylethyl)-n-propylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(1,2-diphenylethyl)-n-propylamine

There total 5 articles about N-(1,2-diphenylethyl)-n-propylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

propylamine (107-10-8,42939-71-9) + benzyl bromide (100-39-0) + benzaldehyde (100-52-7) → N-(1,2-diphenylethyl)-n-propylamine (119486-00-9)

Guidance literature:

propylamine; benzyl bromide; benzaldehyde; With trifluoroacetic acid; zinc; In acetonitrile; for 1h; Inert atmosphere;

With ammonium chloride; In water; acetonitrile;

DOI:10.1021/jo901704s

Reference yield:

[1,2-Diphenyl-eth-(E)-ylidene]-propyl-amine → N-(1,2-diphenylethyl)-n-propylamine (119486-00-9)

Guidance literature:

With sodium cyanoborohydride; zinc(II) chloride; In methanol; toluene; at 25 ℃; for 20h;

DOI:10.1002/chem.200305771

Reference yield:

diphenyl acetylene (501-65-5) → N-(1,2-diphenylethyl)-n-propylamine (119486-00-9)

Guidance literature:

Multi-step reaction with 2 steps

1: [(indenyl)2TiMe₂] / toluene / 3 h / 105 °C

2: 511 mg / NaBH₃CN; ZnCl₂ / toluene; methanol / 20 h / 25 °C

With sodium cyanoborohydride; zinc(II) chloride; bis(indenyl)dimethyl-titanium; In methanol; toluene;

DOI:10.1002/chem.200305771

upstream raw materials:

phenyl benzyl ketone

propylamine

diphenyl acetylene

benzyl bromide

Refernces

• 1、 Heutling, Andreas,Pohlki, Frauke,Doye, Sven. "[Ind2TiMe2]: A general catalyst for the intermolecular hydroamination of alkynes". . p. 3059 - 3071. Retrieved 2007/10/03.