3-[3-(4-(3-acetyloxypropyl)-2-bromo-6-chlorophenoxy)-5-chloro-1-methoxy-4-oxocyclohexa-2,5-dienyl]propyl acetate

Base Information

• Chemical Name: 3-[3-(4-(3-acetyloxypropyl)-2-bromo-6-chlorophenoxy)-5-chloro-1-methoxy-4-oxocyclohexa-2,5-dienyl]propyl acetate
• CAS No.: 704912-88-9
• Molecular Formula: C₂₃H₂₅BrCl₂O₇
• Molecular Weight: 564.257
• Mol file: 704912-88-9.mol

Synonyms:3-[3-(4-(3-acetyloxypropyl)-2-bromo-6-chlorophenoxy)-5-chloro-1-methoxy-4-oxocyclohexa-2,5-dienyl]propyl acetate

Chemical Property of 3-[3-(4-(3-acetyloxypropyl)-2-bromo-6-chlorophenoxy)-5-chloro-1-methoxy-4-oxocyclohexa-2,5-dienyl]propyl acetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[3-(4-(3-acetyloxypropyl)-2-bromo-6-chlorophenoxy)-5-chloro-1-methoxy-4-oxocyclohexa-2,5-dienyl]propyl acetate

There total 4 articles about 3-[3-(4-(3-acetyloxypropyl)-2-bromo-6-chlorophenoxy)-5-chloro-1-methoxy-4-oxocyclohexa-2,5-dienyl]propyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

methanol (67-56-1) + 3-(5-bromo-3-chloro-4-hydroxyphenyl)propyl acetate (704912-87-8) → 3-[3-(4-(3-acetyloxypropyl)-2-bromo-6-chlorophenoxy)-5-chloro-1-methoxy-4-oxocyclohexa-2,5-dienyl]propyl acetate (704912-88-9)

Guidance literature:

With pyridine; lithium perchlorate; Electrochemical reaction;

DOI:10.1016/j.bmc.2005.11.055

Reference yield: 50.0%

methanol (67-56-1) + 3-(5-bromo-3-chloro-4-hydroxyphenyl)propyl acetate (704912-87-8) → 3-(3-bromo-5-chloro-1-methoxy-4-oxocyclohexa-2,5-dienyl)propyl acetate + 3-(5-bromo-3-chloro-4-hydroxyphenyl)-3-methoxypropyl acetate + 3-[3-(4-(3-acetyloxypropyl)-2-bromo-6-chlorophenoxy)-5-chloro-1-methoxy-4-oxocyclohexa-2,5-dienyl]propyl acetate (704912-88-9)

Guidance literature:

With lithium perchlorate; Title compound not separated from byproducts; Electrochemical reaction;

DOI:10.1016/j.bmc.2005.11.055

Reference yield:

3-(4'-hydroxyphenyl)-1-propyl acetate (80373-18-8) → 3-[3-(4-(3-acetyloxypropyl)-2-bromo-6-chlorophenoxy)-5-chloro-1-methoxy-4-oxocyclohexa-2,5-dienyl]propyl acetate (704912-88-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 64 percent / SO₂Cl₂ / 5 h / 0 °C

2: 100 percent / pyridine*HBr₃; pyridine / CHCl₃ / 3 h / 0 °C

3: 50 percent / LiClO₄ / Electrochemical reaction

With pyridine; sulfuryl dichloride; pyridinium perbromide hydrobromide; lithium perchlorate; In chloroform;

DOI:10.1016/j.bmc.2005.11.055

upstream raw materials:

methanol

3-(5-bromo-3-chloro-4-hydroxyphenyl)propyl acetate

acetic acid 3-(3-chloro-4-hydroxy-phenyl)-propyl ester

3-(4'-hydroxyphenyl)-1-propyl acetate

Downstream raw materials:

1-(2,4-bis-methoxymethoxy-phenyl)-3-(3-{4-[3-(2,4-bis-methoxymethoxy-phenyl)-3-oxo-propyl]-2-methoxy-phenoxy}-4-methoxymethoxy-phenyl)-propan-1-one

1-(2,4-bis-methoxymethoxy-phenyl)-3-(3-{4-[3-(2,4-bis-methoxymethoxy-phenyl)-3-hydroxy-propyl]-2-methoxy-phenoxy}-4-methoxymethoxy-phenyl)-propan-1-ol

4,2',4',2''',4'''-Pentahydroxy-3''-methoxy-3-O-4''-tetrahydrobichalcone

3-chloro-2-[3-chloro-2-(methoxymethoxy)-5-(3-(tert-butyldimethylsiloxy)propyl)phenoxy]-5-[3-(tert-butyldimethylsiloxy)propyl]phenol