80373-18-8Relevant academic research and scientific papers
Synthesis and structure/antioxidant activity relationship of novel catecholic antioxidant structural analogues to hydroxytyrosol and its lipophilic esters
Bernini, Roberta,Crisante, Fernanda,Barontini, Maurizio,Tofani, Daniela,Balducci, Valentina,Gambacorta, Augusto
experimental part, p. 7408 - 7416 (2012/10/08)
A large panel of novel catecholic antioxidants and their fatty acid or methyl carbonate esters has been synthesized in satisfactory to good yields through a 2-iodoxybenzoic acid (IBX)-mediated aromatic hydroxylation as the key step. The new catechols are
Selective acylation of alcohols in the presence of phenols
Shah, Muhammad Raza,Ali, Qamar,Hussain, Zahid,Anis, Itrat
experimental part, p. 444 - 448 (2012/04/17)
A versatile method of chemoselective acylation of alcohol has been developed by way of Mitsunobu based strategy. The reaction works under mild conditions and can be selectively employed in presence of phenolic groups and acid sensitivefunctionalities.
Microwave-accelerated selective acylation of (hydroxyalkyl)phenols using acid chlorides
Miyazawa, Toshifumi,Yamamoto, Masato,Maeda, Yuki
experimental part, p. 1092 - 1099 (2009/09/06)
Highly selective acylation of the alcoholic hydroxy group can be achieved with (hydroxyalkyl)phenols carrying both alcoholic and phenolic hydroxyls by the use of the most common acylating agents, acid chlorides, under microwave irradiation. Copyright Tayl
DBU-mediated mild and chemoselective deprotection of aryl silyl ethers and tandem biaryl ether formation
Yeom, Chang-Eun,Kim, Hye Won,Lee, So Young,Kim, B. Moon
, p. 146 - 150 (2008/03/13)
An efficient method for the selective cleavage of aryl silyl ethers is established using 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU). With either 1.0 or 0.10 equivalent of DBU, smooth desilylation of various aryl silyl ethers was accomplished selectively in the presence of alkyl silyl ethers and other base-sensitive groups such as acetate and ester. In addition, direct transformation of aryl silyl ethers into biaryl ethers using a catalytic amount of DBU was possible through tandem desilylation and SNAr reaction with activated aryl fluorides. Georg Thieme Verlag Stuttgart.
Selective acylation of a sterically hindered hydroxyl group of unsymmetrical diols containing a primary hydroxyl group such as 1,5-hexanediol in the presence of silica gel with acetyl chloride
Ogawa, Haruo,Ide, Yuko,Honda, Ryoichi,Chihara, Teiji
, p. 355 - 358 (2007/10/03)
The selective acetylation of sterically hindered hydroxyl groups of 1,5-hexanediol preadsorbed on silica gel was reported. The relation between the adsorption of the diol on SiO2 and its reactivity for selective acetylation was studied. Results demonstrated that unsymmetrical diols get adsorbed on the surface of SiO2 preferentially via a primary OH group, leaving the non-adsorbed OH group available for reaction.
Selective acetylation of aliphatic hydroxyl group in the presence of phenolic hydroxyl group using silica gel supported BF3 catalyst
Das, Biswanath,Venkataiah,Madhusudhan
, p. 249 - 252 (2007/10/03)
Selective acetylation of aliphatic hydroxyl group in the presence of phenolic hydroxyl group was achieved conveniently and efficiently by treatment with EtOAc in the presence of silica gel supported BF3 catalyst.
Heterogeneous catalysis in acetylation of alcohols and phenols promoted by zirconium sulfophenyl phosphonate
Curini, Massimo,Epifano, Francesco,Marcotullio, Maria Carla,Rosati, Ornelio,Rossi, Monia
, p. 1319 - 1329 (2007/10/03)
Layered zirconium sulfophenyl phosphonate was found to be an efficient heterogeneous catalyst for the acetylation of alcohols and phenols.
Lipase-catalysed chemoselective monoacetylation of hydroxyalkylphenols and chemoselective removal of a single acetyl group from their diacetates
Allevi, Pietro,Ciuffreda, Pierangela,Longo, Alessandra,Anastasia, Mario
, p. 2915 - 2924 (2007/10/03)
It was demonstrated that Pseudomonas cepacia PS lipase adsorbed on Celite, has the ability to catalyse the chemoselective monoacetylation of various hydroxyalkylphenols or the chemoselective removal of a single acetyl group from the corresponding acetate.
Microwave-assisted Deacetylation on Alumina: a Simple Deprotection Method
Varma, Rajender S.,Varma, Manju,Chatterjee, Arnab K.
, p. 999 - 1000 (2007/10/02)
A simple high-yielding method for the deprotection of acetylated phenols and alcohols is described which occurs under mild conditions on an alumina surface using microwave irradiation.
