(Z)-methyl N-phenylbenzimidate

Base Information

• Chemical Name: (Z)-methyl N-phenylbenzimidate
• CAS No.: 64141-84-0
• Molecular Formula: C₁₄H₁₃NO
• Molecular Weight: 211.263
• Mol file: 64141-84-0.mol

Synonyms:(Z)-methyl N-phenylbenzimidate

Chemical Property of (Z)-methyl N-phenylbenzimidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-methyl N-phenylbenzimidate

There total 4 articles about (Z)-methyl N-phenylbenzimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

methanol (67-56-1) + N-phenylbenzimidoyl chloride (38430-03-4) → (Z)-methyl N-phenylbenzimidate (64141-84-0)

Guidance literature:

methanol; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.5h; Inert atmosphere;

N-phenylbenzimidoyl chloride; In tetrahydrofuran; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1002/anie.201306360

Reference yield: 65.0%

sodium methylate (124-41-4) + N-phenylbenzimidoyl chloride (38430-03-4) → (Z)-methyl N-phenylbenzimidate (64141-84-0)

Guidance literature:

In benzene;

Reference yield:

N-phenyl benzoyl amide (93-98-1,5705-51-1) → (Z)-methyl N-phenylbenzimidate (64141-84-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: thionyl chloride / 24 h / Reflux; Inert atmosphere

2.1: sodium hydride / tetrahydrofuran / 0.5 h / 0 °C / Inert atmosphere

2.2: 24 h / 20 °C / Inert atmosphere

With thionyl chloride; sodium hydride; In tetrahydrofuran;

DOI:10.1002/anie.201306360

upstream raw materials:

sodium methylate

N-phenylbenzimidoyl chloride

N-phenyl benzoyl amide

methanol

Downstream raw materials:

aniline

orthobenzoic acid trimethyl ester

benzoic acid methyl ester

methanol