2-(Hydroxyimino)-N-(o-tolyl)acetamide

Base Information

• Chemical Name: 2-(Hydroxyimino)-N-(o-tolyl)acetamide
• CAS No.: 1132-03-2
• Molecular Formula: C9H10 N2 O2
• Molecular Weight: 178.191
• Hs Code.: 2928000090
• European Community (EC) Number: 214-472-2
• DSSTox Substance ID: DTXSID301255209
• Mol file: 1132-03-2.mol

Synonyms:2-(Hydroxyimino)-N-(o-tolyl)acetamide;1132-03-2;2-(Hydroxyimino)-N-(2-methylphenyl)acetamide;Acetamide, 2-(hydroxyimino)-N-(2-methylphenyl)-;Enamine_000498;NCIMech_000307;Oprea1_761145;Oprea1_808557;XLFBDBCQQNVKHU-UHFFFAOYSA-N;DTXSID301255209;AKOS028111825;NCI60_008007;PD028258;FT-0683915

Chemical Property of 2-(Hydroxyimino)-N-(o-tolyl)acetamide

Chemical Property:

• PSA: 61.69000
• Density: 1.17g/cm³
• LogP: 1.46650
• Storage Temp.: 2-8°C
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 178.074227566
• Heavy Atom Count: 13
• Complexity: 204

Purity/Quality:

98% ^*data from raw suppliers

ALPHA-HYDROXYIMINO-O-ACETOTOLUIDIDE AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=CC=C1NC(=O)C=NO

Technology Process of 2-(Hydroxyimino)-N-(o-tolyl)acetamide

There total 6 articles about 2-(Hydroxyimino)-N-(o-tolyl)acetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.5%

C9H10N2O2 → 2-(hydroxyimino)-N-(2-methylphenyl)acetamide (1132-03-2)

Guidance literature:

Cooling with ice;

Reference yield: 76.0%

chloral hydrate (302-17-0) + o-toluidine (95-53-4) → 2-(hydroxyimino)-N-(2-methylphenyl)acetamide (1132-03-2)

Guidance literature:

With hydrogenchloride; hydroxylamine hydrochloride; sodium sulfate; In water; at 55 ℃; for 12h;

Reference yield: 65.0%

→ 2-(hydroxyimino)-N-(2-methylphenyl)acetamide (1132-03-2)

Guidance literature:

upstream raw materials:

chloral hydrate

o-toluidine

chloral

chloral ethyl hemiacetal

Downstream raw materials:

7-methyl-1H-indole-2,3-dione

3-methylantranilic acid

2-amino-5-chloro-3-methylbenzoic acid

2-amino-3-methyl-5-chlorobenzoyl-N-methylamine