sodium N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}dithiocarbamate

Base Information

• Chemical Name: sodium N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}dithiocarbamate
• CAS No.: 524678-13-5
• Molecular Formula: C₁₄H₂₀N₃OS₂*Na
• Molecular Weight: 333.454
• Mol file: 524678-13-5.mol

Synonyms:sodium N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}dithiocarbamate

Chemical Property of sodium N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}dithiocarbamate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of sodium N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}dithiocarbamate

There total 2 articles about sodium N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}dithiocarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.86%

carbon disulfide (75-15-0,12122-00-8) + 1-(2-aminoethyl)-4-(2-methoxyphenyl)piperazine (40255-48-9) → sodium N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}dithiocarbamate (524678-13-5)

Guidance literature:

With sodium hydroxide; In water; acetone; at 4 ℃; Cooling with ice;

DOI:10.1007/s00775-010-0712-4

Reference yield:

1-(2-methoxyphenyl)piperazine hydrochloride (5464-78-8) → sodium N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}dithiocarbamate (524678-13-5)

Guidance literature:

Multi-step reaction with 3 steps

1.1: triethylamine / dichloromethane / 20 °C

2.1: hydrogenchloride / dichloromethane; water / 2 h / 20 °C

2.2: pH 9

3.1: sodium hydroxide / water; acetone / 4 °C / Cooling with ice

With hydrogenchloride; triethylamine; sodium hydroxide; In dichloromethane; water; acetone;

DOI:10.1007/s00775-010-0712-4

Reference yield: 66.0%

[ReOCl3(PPh3)2] + (2-mercaptoethyl)diphenylphosphine (3190-79-2) + sodium N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}dithiocarbamate (524678-13-5) → C42H48N3OP2ReS4

Guidance literature:

In ethanol; toluene; for 1h; Reflux; Inert atmosphere; Schlenk technique;

DOI:10.1021/ic400094s

upstream raw materials:

carbon disulfide

1-(2-aminoethyl)-4-(2-methoxyphenyl)piperazine

1-(2-methoxyphenyl)piperazine hydrochloride