{(Z)-2-[6-(2-Methoxy-ethoxy)-5-phenylselanyl-tetrahydro-pyran-2-yl]-1-phenylsulfanyl-vinyl}-trimethyl-silane

Base Information

• Chemical Name: {(Z)-2-[6-(2-Methoxy-ethoxy)-5-phenylselanyl-tetrahydro-pyran-2-yl]-1-phenylsulfanyl-vinyl}-trimethyl-silane
• CAS No.: 77890-89-2
• Molecular Formula: C₂₅H₃₄O₃SSeSi
• Molecular Weight: 521.655
• Mol file: 77890-89-2.mol

Synonyms:{(Z)-2-[6-(2-Methoxy-ethoxy)-5-phenylselanyl-tetrahydro-pyran-2-yl]-1-phenylsulfanyl-vinyl}-trimethyl-silane

Chemical Property of {(Z)-2-[6-(2-Methoxy-ethoxy)-5-phenylselanyl-tetrahydro-pyran-2-yl]-1-phenylsulfanyl-vinyl}-trimethyl-silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {(Z)-2-[6-(2-Methoxy-ethoxy)-5-phenylselanyl-tetrahydro-pyran-2-yl]-1-phenylsulfanyl-vinyl}-trimethyl-silane

There total 6 articles about {(Z)-2-[6-(2-Methoxy-ethoxy)-5-phenylselanyl-tetrahydro-pyran-2-yl]-1-phenylsulfanyl-vinyl}-trimethyl-silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

Phenylselenyl chloride (5707-04-0) + 2-methoxy-ethanol (109-86-4,95507-80-5) + [(Z)-2-(3,4-Dihydro-2H-pyran-2-yl)-1-phenylsulfanyl-vinyl]-trimethyl-silane (77890-82-5) → {(Z)-2-[6-(2-Methoxy-ethoxy)-5-phenylselanyl-tetrahydro-pyran-2-yl]-1-phenylsulfanyl-vinyl}-trimethyl-silane (77890-89-2)

Guidance literature:

With pyridine; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1021/jo00193a015

Reference yield: 92.0%

Phenylselenyl chloride (5707-04-0) + 2-methoxy-ethanol (109-86-4,95507-80-5) + [(E)-2-(3,4-Dihydro-2H-pyran-2-yl)-1-phenylsulfanyl-vinyl]-trimethyl-silane (77890-81-4) → {(Z)-2-[6-(2-Methoxy-ethoxy)-5-phenylselanyl-tetrahydro-pyran-2-yl]-1-phenylsulfanyl-vinyl}-trimethyl-silane (77890-89-2)

Guidance literature:

With pyridine; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1021/jo00193a015

Reference yield:

acrolein dimer (100-73-2) → {(Z)-2-[6-(2-Methoxy-ethoxy)-5-phenylselanyl-tetrahydro-pyran-2-yl]-1-phenylsulfanyl-vinyl}-trimethyl-silane (77890-89-2)

Guidance literature:

Multi-step reaction with 2 steps

1: tetrahydrofuran; hexane / Ambient temperature

2: 92 percent / pyridine / CH₂Cl₂ / 0.5 h / 0 °C

With pyridine; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1021/jo00193a015

upstream raw materials:

Phenylselenyl chloride

2-methoxy-ethanol

[(E)-2-(3,4-Dihydro-2H-pyran-2-yl)-1-phenylsulfanyl-vinyl]-trimethyl-silane

[(Z)-2-(3,4-Dihydro-2H-pyran-2-yl)-1-phenylsulfanyl-vinyl]-trimethyl-silane

Downstream raw materials:

(1S,2S,4S,6S)-4-((R)-2-Benzenesulfonyl-1-methyl-ethyl)-2-(2-methoxy-ethoxy)-3,7-dioxa-bicyclo[4.1.0]heptane

(E)-(2R,5S,6R)-7-Benzenesulfonyl-2,3,3-trimethoxy-6,8-dimethyl-undec-9-ene-1,5-diol

(1S,2S,4S,6S)-4-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-methoxy-ethoxy)-3,7-dioxa-bicyclo[4.1.0]heptane

(3S,4R,6S)-6-((E)-(R)-2-Benzenesulfonyl-1,3-dimethyl-hex-4-enyl)-2-(2-chloro-ethoxy)-3-methoxy-tetrahydro-pyran-4-ol