4-((N-(phenylsulfonyl)phenylsulfonamido)methyl)phenyl pivalate

Base Information

• Chemical Name: 4-((N-(phenylsulfonyl)phenylsulfonamido)methyl)phenyl pivalate
• CAS No.: 1361033-75-1
• Molecular Formula: C₂₄H₂₅NO₆S₂
• Molecular Weight: 487.598
• Mol file: 1361033-75-1.mol

Synonyms:4-((N-(phenylsulfonyl)phenylsulfonamido)methyl)phenyl pivalate

Chemical Property of 4-((N-(phenylsulfonyl)phenylsulfonamido)methyl)phenyl pivalate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-((N-(phenylsulfonyl)phenylsulfonamido)methyl)phenyl pivalate

There total 2 articles about 4-((N-(phenylsulfonyl)phenylsulfonamido)methyl)phenyl pivalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

(4-Methylphenyl)-pivaloat (69120-23-6) + N-fluorobis(benzenesulfon)imide (133745-75-2) → 4-((N-(phenylsulfonyl)phenylsulfonamido)methyl)phenyl pivalate (1361033-75-1)

Guidance literature:

With 1,10-Phenanthroline; copper(l) chloride; In 1,2-dichloro-ethane; at 110 ℃; for 3h; regioselective reaction;

DOI:10.1002/anie.201107427

Reference yield:

p-cresol (106-44-5) + pivaloyl chloride (3282-30-2) → 4-((N-(phenylsulfonyl)phenylsulfonamido)methyl)phenyl pivalate (1361033-75-1)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / dichloromethane / 20 °C

2: 1,10-Phenanthroline; copper(l) chloride / 1,2-dichloro-ethane / 3 h / 110 °C

With 1,10-Phenanthroline; potassium carbonate; copper(l) chloride; In dichloromethane; 1,2-dichloro-ethane;

DOI:10.1002/anie.201107427

upstream raw materials:

p-cresol

pivaloyl chloride

(4-Methylphenyl)-pivaloat

N-fluorobis(benzenesulfon)imide