Piperazinone, 4-benzoyl-1-(phenylmethyl)-

Base Information

Chemical Name:Piperazinone, 4-benzoyl-1-(phenylmethyl)-
CAS No.:107235-69-8
Molecular Formula:C18H18 N2 O2
Molecular Weight:294.3477
Hs Code.:
DSSTox Substance ID:DTXSID50147974
Wikidata:Q83013410
Mol file:107235-69-8.mol

Synonyms:BRN 4513114;Piperazinone, 4-benzoyl-1-(phenylmethyl)-;4-Benzoyl-1-(phenylmethyl)piperazinone;107235-69-8;DTXSID50147974;4-benzoyl-1-benzyl-2-piperazinone;LS-113808

Suppliers and Price of Piperazinone, 4-benzoyl-1-(phenylmethyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Piperazinone, 4-benzoyl-1-(phenylmethyl)-

Chemical Property:

Vapor Pressure:3.26E-11mmHg at 25°C
Boiling Point:527.4°C at 760 mmHg
Flash Point:249.8°C
Density:1.224g/cm³
XLogP3:2.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:294.136827821
Heavy Atom Count:22
Complexity:398

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CN(C(=O)CN1C(=O)C2=CC=CC=C2)CC3=CC=CC=C3

Technology Process of Piperazinone, 4-benzoyl-1-(phenylmethyl)-

There total 5 articles about Piperazinone, 4-benzoyl-1-(phenylmethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 67630-76-6
N-benzyl-N'-benzoylethylenediamine

: 79-04-9
chloroacetyl chloride

: 107235-69-8
4-Benzoyl-1-benzyl-2-piperazinone

Guidance literature:: With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In benzene; at 55 - 60 ℃; for 1h;
DOI:10.1007/BF00472293

Reference yield: 82.0%

: 78551-58-3
1-(Phenylmethyl)piperazinone hydrochloride

: 98-88-4
benzoyl chloride

: 107235-69-8
4-Benzoyl-1-benzyl-2-piperazinone

Guidance literature:: With triethylamine; In chloroform; at 20 ℃; for 1h;
DOI:10.1007/BF00542783

Reference yield:

: 107235-77-8
N-Benzyl-N,N'-bis(chloroacetyl)ethylendiamine

: 107235-69-8
4-Benzoyl-1-benzyl-2-piperazinone

Guidance literature:: Multi-step reaction with 3 steps

1: 35 percent / potassium tert-butylate / 2-methyl-propan-2-ol / 0.33 h / Ambient temperature

2: 60 percent / o-phenylendiamine / aq. ethanol / 2 h / Heating

3: 82 percent / triethylamine / CHCl₃ / 1 h / 20 °C

With potassium tert-butylate; triethylamine; 1,2-diamino-benzene; In ethanol; chloroform; tert-butyl alcohol;
DOI:10.1007/BF00542783