4-(4-Biphenylyl)benzophenone

Base Information

• Chemical Name: 4-(4-Biphenylyl)benzophenone
• CAS No.: 5623-42-7
• Molecular Formula: C₂₅H₁₈O
• Molecular Weight: 334.417
• European Community (EC) Number: 660-456-7
• DSSTox Substance ID: DTXSID40402064
• Wikidata: Q82205420
• Mol file: 5623-42-7.mol

Synonyms:4-(4-BIPHENYLYL)BENZOPHENONE;5623-42-7;SCHEMBL13534566;DTXSID40402064;AKOS024338787

Chemical Property of 4-(4-Biphenylyl)benzophenone

Chemical Property:

• XLogP3: 6.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 334.135765193
• Heavy Atom Count: 26
• Complexity: 427

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-(4-BIPHENYLYL)BENZOPHENONE AldrichCPR ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=CC=C(C=C2)C3=CC=C(C=C3)C(=O)C4=CC=CC=C4

Technology Process of 4-(4-Biphenylyl)benzophenone

There total 7 articles about 4-(4-Biphenylyl)benzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

1-[3-(4-biphenylyl)-5-(1-piperidinyl)-2,4-pentadienylidene]piperidinium hexafluorophosphate + acetophenone (98-86-2) → 4-(4-biphenylyl)benzophenone (5623-42-7)

Guidance literature:

With sodium t-butanolate; In tetrahydrofuran; at 120 ℃; for 10h; Inert atmosphere;

DOI:10.1039/c9cc04012a

Reference yield:

N-(2,4-dinitrophenyl)-4-(4-biphenylyl)pyridinium chloride → 4-(4-biphenylyl)benzophenone (5623-42-7)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 2 h / 80 °C / Inert atmosphere

2: sodium t-butanolate / tetrahydrofuran / 10 h / 120 °C / Inert atmosphere

With sodium t-butanolate; In tetrahydrofuran; ethanol;

DOI:10.1039/c9cc04012a

Reference yield:

4-([1,1’-biphenyl]-4-yl)pyridine (861024-61-5) → 4-(4-biphenylyl)benzophenone (5623-42-7)

Guidance literature:

Multi-step reaction with 3 steps

1: acetone / 24 h / Reflux; Inert atmosphere

2: ethanol / 2 h / 80 °C / Inert atmosphere

3: sodium t-butanolate / tetrahydrofuran / 10 h / 120 °C / Inert atmosphere

With sodium t-butanolate; In tetrahydrofuran; ethanol; acetone;

DOI:10.1039/c9cc04012a

upstream raw materials:

[1,1';4',1'']terphenyl

benzoyl chloride

benzonitrile

(4-bromophenyl)(phenyl)methanone

Downstream raw materials:

1,2-bis(4'-phenylbiphenyl-4-yl)-1,2-diphenylethene