1-Methylpseudouridine

Base Information

Chemical Name:1-Methylpseudouridine
CAS No.:13860-38-3
Molecular Formula:C10H14 N2 O6
Molecular Weight:258.231
Hs Code.:
UNII:09RAD4M6WF
DSSTox Substance ID:DTXSID50160724
Nikkaji Number:J13.862B
Wikipedia:N1-Methylpseudouridine
Wikidata:Q27109108
Metabolomics Workbench ID:53669
Mol file:13860-38-3.mol

Synonyms:1-methylpseudouridine;N1-methyl-pseudouridine

Suppliers and Price of 1-Methylpseudouridine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
1-Methylpseudouridine
1mg
$ 347.00

Biosynth Carbosynth
1-Methylpseudouridine
2 mg
$ 100.00

Biosynth Carbosynth
1-Methylpseudouridine
1 mg
$ 60.00

Biosynth Carbosynth
1-Methylpseudouridine
0.05 g
$ 110.00

Biosynth Carbosynth
1-Methylpseudouridine
0.25 g
$ 299.78

Biosynth Carbosynth
1-Methylpseudouridine
10 mg
$ 275.00

Biosynth Carbosynth
1-Methylpseudouridine
25 mg
$ 475.00

Biosynth Carbosynth
1-Methylpseudouridine
5 mg
$ 175.00

Biosynth Carbosynth
1-Methylpseudouridine
0.1 g
$ 170.00

Biosynth Carbosynth
1-Methylpseudouridine
1 g
$ 1087.60

Total 53 raw suppliers

Chemical Property of 1-Methylpseudouridine

Chemical Property:

Boiling Point:°Cat760mmHg
Flash Point:°C
PSA：124.78000
Density:1.576g/cm³
LogP:-2.77240
XLogP3:-2.6
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:2
Exact Mass:258.08518617
Heavy Atom Count:18
Complexity:409

Purity/Quality:

99.3% ^*data from raw suppliers

1-Methylpseudouridine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C=C(C(=O)NC1=O)C2C(C(C(O2)CO)O)O
Isomeric SMILES:CN1C=C(C(=O)NC1=O)[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O
Description N1-Methylpseudouridine is a modified nucleoside used for enhancing mRNA translation. Incorporation of N1-Methylpseudouridine into mRNA turns off the immune/eIF2α phosphorylation-dependent inhibition of translation, and increases ribosome pausing and density on the mRNA, thus dramatically facilitating the translation process. N1-Methylpseudouridine outperforms several other modified nucleosides (e.g. 5-Methylcytidine) and corresponding combinations in terms of translation capacity.

Technology Process of 1-Methylpseudouridine

There total 9 articles about 1-Methylpseudouridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%