(3S)-N-cyclopropyl-3-((R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)-ethyl)amino)propanamido)-2-hydroxypentanamide

Base Information

Chemical Name:(3S)-N-cyclopropyl-3-((R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)-ethyl)amino)propanamido)-2-hydroxypentanamide
CAS No.:1408001-11-5
Molecular Formula:C₂₃H₃₁F₄N₃O₅S
Molecular Weight:537.576
Hs Code.:

Synonyms:(3S)-N-cyclopropyl-3-((R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)-ethyl)amino)propanamido)-2-hydroxypentanamide

Suppliers and Price of (3S)-N-cyclopropyl-3-((R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)-ethyl)amino)propanamido)-2-hydroxypentanamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S)-N-cyclopropyl-3-((R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)-ethyl)amino)propanamido)-2-hydroxypentanamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S)-N-cyclopropyl-3-((R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)-ethyl)amino)propanamido)-2-hydroxypentanamide

There total 5 articles about (3S)-N-cyclopropyl-3-((R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)-ethyl)amino)propanamido)-2-hydroxypentanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7646-93-7
potassium hydrogensulfate

: 849094-11-7
(R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)amino)propanoic acid

: 3S-amino-N-cyclopropyl-2-hydroxypentanamide hydrochloride

: 108-18-9
diisopropylamine

: 1408001-11-5
(3S)-N-cyclopropyl-3-((R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)-ethyl)amino)propanamido)-2-hydroxypentanamide

Guidance literature:: With N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In diethyl ether; hexane; dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 655-32-3
2,2,2-trifluoro-1-(4-fluorophenyl)ethanone

: 1408001-11-5
(3S)-N-cyclopropyl-3-((R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)-ethyl)amino)propanamido)-2-hydroxypentanamide

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / isopropyl alcohol; acetonitrile

2: hydrogenchloride / zinc(II) chloride / 1,2-dimethoxyethane; acetonitrile; lithium borohydride

3: dihydrogen peroxide / ethyl acetate; toluene; hexane

4: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / dichloromethane; N,N-dimethyl-formamide; hexane; diethyl ether

With hydrogenchloride; dihydrogen peroxide; potassium carbonate; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; zinc(II) chloride; In 1,2-dimethoxyethane; lithium borohydride; diethyl ether; hexane; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; isopropyl alcohol; toluene; acetonitrile;

Reference yield:

: (R)-methyl2-amino-3-((cyclopropylmethyl)thio)propanoate hydrochloride

: 1408001-11-5
(3S)-N-cyclopropyl-3-((R)-3-((cyclopropylmethyl)sulfonyl)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)-ethyl)amino)propanamido)-2-hydroxypentanamide

Guidance literature:: Multi-step reaction with 4 steps

1: potassium carbonate / isopropyl alcohol; acetonitrile

2: hydrogenchloride / zinc(II) chloride / 1,2-dimethoxyethane; acetonitrile; lithium borohydride

3: dihydrogen peroxide / ethyl acetate; toluene; hexane

4: N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / dichloromethane; N,N-dimethyl-formamide; hexane; diethyl ether

With hydrogenchloride; dihydrogen peroxide; potassium carbonate; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; zinc(II) chloride; In 1,2-dimethoxyethane; lithium borohydride; diethyl ether; hexane; dichloromethane; ethyl acetate; N,N-dimethyl-formamide; isopropyl alcohol; toluene; acetonitrile;