L-Cysteine, S-(cyclopropylmethyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-

Base Information

Chemical Name:L-Cysteine, S-(cyclopropylmethyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-
CAS No.:849094-18-4
Molecular Formula:C15H17F4NO2S
Molecular Weight:351.36000
Hs Code.:

Synonyms:2(R)-[2,2,2-trifluoro-1(S)-(4-fluorophenyl)ethylamino]-3-(cyclopropylmethanesulfanyl)propionic acid;2(R)-[2,2,2-trifluoro-1(RS)-(4-fluorophenyl)ethylamino]-3-cyclopropylmethanesulfanylpropionic acid;

Suppliers and Price of L-Cysteine, S-(cyclopropylmethyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of L-Cysteine, S-(cyclopropylmethyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-

Chemical Property:

PSA：74.63000
LogP:4.00600

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of L-Cysteine, S-(cyclopropylmethyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]-

There total 4 articles about L-Cysteine, S-(cyclopropylmethyl)-N-[(1S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 880762-37-8
2(R)-[2,2,2-trifluoro-1(S)-(4-fluorophenyl)ethylamino]-3-tritylsulfanyl-propionic acid

: 7051-34-5
cyclopropylcarbinyl bromide

: 1408001-10-4
2(R)-[2,2,2-trifluoro-1(R)-(4-fluorophenyl)ethylamino]-3-(cyclopropylmethanesulfanyl)propionic acid

: 849094-18-4
(R)-3-((cyclopropylmethyl)thio)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)amino)propanoic acid

Guidance literature:: 2(R)-[2,2,2-trifluoro-1(S)-(4-fluorophenyl)ethylamino]-3-tritylsulfanyl-propionic acid; 2(R)-[2,2,2-trifluoro-1(R)-(4-fluorophenyl)ethylamino]-3-tritylsulfanyl-propionic acid; With triethylsilane; trifluoroacetic acid; In dichloromethane; at 20 ℃; for 16h;

cyclopropylcarbinyl bromide; In 1,4-dioxane; water; at 20 ℃; for 16h;

Reference yield:

: zinc(II) tetrahydroborate

: 124-38-9,18923-20-1
carbon dioxide

: 1408001-09-1
potassium (R,Z)-3-((cyclopropylmethyl)thio)-2-((2,2,2-trifluoro-1-(4-fluorophenyl)ethylidene)-amino)propanoate

: 849094-18-4
(R)-3-((cyclopropylmethyl)thio)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)amino)propanoic acid

Guidance literature:: With hydrogenchloride; zinc(II) chloride; In 1,2-dimethoxyethane; lithium borohydride; acetonitrile;

Reference yield:

: (R)-methyl2-amino-3-((cyclopropylmethyl)thio)propanoate hydrochloride

: 849094-18-4
(R)-3-((cyclopropylmethyl)thio)-2-(((S)-2,2,2-trifluoro-1-(4-fluorophenyl)ethyl)amino)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / isopropyl alcohol; acetonitrile

2: hydrogenchloride / zinc(II) chloride / 1,2-dimethoxyethane; acetonitrile; lithium borohydride

With hydrogenchloride; potassium carbonate; zinc(II) chloride; In 1,2-dimethoxyethane; lithium borohydride; isopropyl alcohol; acetonitrile;