(1S)-2-O-methanesulfonyl-1-O-(Z-prop-1'-en-1'-yl)-1-phenyl-1,2-ethanediol

Base Information

Chemical Name:(1S)-2-O-methanesulfonyl-1-O-(Z-prop-1'-en-1'-yl)-1-phenyl-1,2-ethanediol
CAS No.:685835-95-4
Molecular Formula:C₁₂H₁₆O₄S
Molecular Weight:256.323
Hs Code.:

Synonyms:(1S)-2-O-methanesulfonyl-1-O-(Z-prop-1'-en-1'-yl)-1-phenyl-1,2-ethanediol

Suppliers and Price of (1S)-2-O-methanesulfonyl-1-O-(Z-prop-1'-en-1'-yl)-1-phenyl-1,2-ethanediol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S)-2-O-methanesulfonyl-1-O-(Z-prop-1'-en-1'-yl)-1-phenyl-1,2-ethanediol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S)-2-O-methanesulfonyl-1-O-(Z-prop-1'-en-1'-yl)-1-phenyl-1,2-ethanediol

There total 4 articles about (1S)-2-O-methanesulfonyl-1-O-(Z-prop-1'-en-1'-yl)-1-phenyl-1,2-ethanediol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 124-63-0
methanesulfonyl chloride

: 685836-12-8
(1S)-1-phenyl-1-O-(Z-prop-1'-en-1'-yl)-1,2-ethanediol

: 685835-95-4
(1S)-2-O-methanesulfonyl-1-O-(Z-prop-1'-en-1'-yl)-1-phenyl-1,2-ethanediol

Guidance literature:: With triethylamine; In dichloromethane; at 10 ℃; for 13h;
DOI:10.1016/j.bmc.2003.10.043

Reference yield:

: 25779-13-9
(S)-1-phenyl-1,2-ethanediol

: 685835-95-4
(1S)-2-O-methanesulfonyl-1-O-(Z-prop-1'-en-1'-yl)-1-phenyl-1,2-ethanediol

Guidance literature:: Multi-step reaction with 5 steps

1: CH₂Cl₂ / 3 h

2: NaH / dimethylformamide; various solvent(s) / 2 h / 20 °C

3: p-TsOH / methanol / 1 h

4: t-BuOK / dimethylsulfoxide / 1.5 h / 55 °C

5: 96 percent / Et₃N / CH₂Cl₂ / 13 h / 10 °C

With potassium tert-butylate; sodium hydride; toluene-4-sulfonic acid; triethylamine; In methanol; dichloromethane; dimethyl sulfoxide; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2003.10.043

Reference yield:

: 95237-09-5
(1S)-1-O-allyl-1-phenyl-1,2-ethanediol

: 685835-95-4
(1S)-2-O-methanesulfonyl-1-O-(Z-prop-1'-en-1'-yl)-1-phenyl-1,2-ethanediol

Guidance literature:: Multi-step reaction with 2 steps

1: t-BuOK / dimethylsulfoxide / 1.5 h / 55 °C

2: 96 percent / Et₃N / CH₂Cl₂ / 13 h / 10 °C

With potassium tert-butylate; triethylamine; In dichloromethane; dimethyl sulfoxide;
DOI:10.1016/j.bmc.2003.10.043