Galactitol

Base Information

• Chemical Name: Galactitol
• CAS No.: 608-66-2
• Deprecated CAS: 18089-21-9,40742-76-5,362631-40-1,1315281-36-7,904746-81-2,1644285-24-4,1810040-83-5,2075831-00-2,1315281-36-7,362631-40-1,40742-76-5,904746-81-2
• Molecular Formula: C6H14O6
• Molecular Weight: 182.174
• Hs Code.: 29054990
• European Community (EC) Number: 210-165-2
• UNII: 113ZQ1Y7DD
• DSSTox Substance ID: DTXSID1046051
• Nikkaji Number: J7.011D
• Wikipedia: Galactitol
• Wikidata: Q420367
• Metabolomics Workbench ID: 37077
• ChEMBL ID: CHEMBL1773904
• Mol file: 608-66-2.mol

Synonyms:Dulcitol;Galactitol

Chemical Property of Galactitol

Chemical Property:

• Appearance/Colour: White crystalline powder
• Vapor Pressure: <0.1 mm Hg ( 25 °C)
• Melting Point: 98-100 °C(lit.)
• Refractive Index: n20/D 1.46
• Boiling Point: 494.9 °C at 760 mmHg
• PKA: pKa 13.57(H2O t = 18 t = 0)(Approximate);14.14(H2O t = 18 t = 0)(Approximate)
• Flash Point: 292.5 °C
• PSA: 121.38000
• Density: 1.596 g/cm³
• LogP: -3.58540
• Storage Temp.: Store at RT.
• Sensitive.: Hygroscopic
• Solubility.: H2O: 1 M at 20 °C, clear, colorless
• Water Solubility.: SOLUBLE IN HOT WATER
• XLogP3: -3.1
• Hydrogen Bond Donor Count: 6
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 182.07903816
• Heavy Atom Count: 12
• Complexity: 105

Purity/Quality:

98%,99%, ^*data from raw suppliers

Dulcitol 99+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 8-24/25-36/37-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Biological Agents -> Monosaccharides and Derivatives
• Canonical SMILES: C(C(C(C(C(CO)O)O)O)O)O
• Isomeric SMILES: C([C@H]([C@@H]([C@@H]([C@H](CO)O)O)O)O)O
• Uses: Dulcitol is important in studies related to cataract formation, hepatosplenμly and mental retardation. It is used as a substrate to identify, differentiate and characterize galactitol dehydrogenase(s). It is also used as a reference compound in analytical procedures developed to analyze sugar alcohols in plants and food. Dulcitol is the reduction product of Galactose. An increase in the level of Dulcitol is often a result of metabolism defect caused by a defect in galactose-1-phosphate uridylyltransferase (an autosomal recessive disorder). Dulcitol buildup can also lead t sorbitol absorbs moisture from the air to prevent skin dryness, and leaves the skin feeling smooth and velvety. However, if the skin’s moisture content is greater than that of the atmosphere, it will draw moisture out of the skin, thereby increasing the feeling of dryness. Sorbitol is used by formulators as a replacement for glycerin in emulsions, ointments, and various cosmetic creams. It is obtained from the leaves and in some cases the berries of mountain ash. Sorbitol also occurs in other berries, cherries, plums, pears, apples, seaweed, and algae.

Technology Process of Galactitol

There total 117 articles about Galactitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.2%

cellulose (9004-34-6) → propylene glycol (57-55-6,63625-56-9) + ethylene glycol (107-21-1) + isopropyl alcohol (67-63-0,8013-70-5) + sorbitol (50-70-4,69-65-8,87-78-5,133-43-7,488-44-8,488-45-9,608-66-2,643-01-6,643-03-8,5552-13-6,6706-59-8,24557-79-7,25878-23-3,26566-34-7,45007-61-2,60660-56-2,60660-57-3,60660-58-4,132747-27-4)

Guidance literature:

With water; at 220 ℃; for 0.5h; under 52505.3 Torr; Temperature; Pressure;

Reference yield: 33.6%

cellulose (9004-34-6) → propylene glycol (57-55-6,63625-56-9) + isopropyl alcohol (67-63-0,8013-70-5) + sorbitol (50-70-4,69-65-8,87-78-5,133-43-7,488-44-8,488-45-9,608-66-2,643-01-6,643-03-8,5552-13-6,6706-59-8,24557-79-7,25878-23-3,26566-34-7,45007-61-2,60660-56-2,60660-57-3,60660-58-4,132747-27-4)

Guidance literature:

With water; at 220 ℃; for 0.5h; under 45004.5 Torr; Temperature; Pressure;

Reference yield: 15.8%

cellulose (9004-34-6) → propylene glycol (57-55-6,63625-56-9) + sorbitol (50-70-4,69-65-8,87-78-5,133-43-7,488-44-8,488-45-9,608-66-2,643-01-6,643-03-8,5552-13-6,6706-59-8,24557-79-7,25878-23-3,26566-34-7,45007-61-2,60660-56-2,60660-57-3,60660-58-4,132747-27-4)

Guidance literature:

With hydrogen; In water; at 239.84 ℃; for 4h; under 30003 Torr;

DOI:10.1039/c2gc35685f

upstream raw materials:

hex-3c-ene-1,2,5,6-tetraol

ethanol

D-Galactose

aldehydo-L-Galactose

Downstream raw materials:

galactitol; dulcitol

5-hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

L-Lactic acid

DL-altritol

Refernces

• 1、 Kuang, Haixue,Su, Yang,Yang, Bingyou,Xia, Yonggang,Wang, Qiuhong,Wang, Zhibin,Yu, Zhengfan. "Three new cycloartenol triterpenoid saponins from the roots of cimicifuga simplex wormsk". . p. 4348 - 4357. Retrieved 2011.
• 2、 Tindall, Daniel J.,Mader, Steffen,Kindler, Alois,Rominger, Frank,Hashmi, A. Stephen K.,Schaub, Thomas. "Selective and Scalable Synthesis of Sugar Alcohols by Homogeneous Asymmetric Hydrogenation of Unprotected Ketoses". supporting information. p. 721 - 725. Retrieved 2020/10/19.
• 3、 Huang, Linlin,Li, Fei,Li, Quanhong,Liang, Li,Wei, Yunlu,Yu, Guoyong. "A novel low-molecular-mass pumpkin polysaccharide: Structural characterization, antioxidant activity, and hypoglycemic potential". . . Retrieved 2020/10/02.