Methyl betulinate

Base Information

Chemical Name:Methyl betulinate
CAS No.:2259-06-5
Molecular Formula:C₃₁H₅₀O₃
Molecular Weight:470.736
Hs Code.:
European Community (EC) Number:218-857-6
Nikkaji Number:J109.369J
Wikidata:Q105337617
Metabolomics Workbench ID:130072
ChEMBL ID:CHEMBL295602
Mol file:2259-06-5.mol

Synonyms:betulinic acid methyl ester

Suppliers and Price of Methyl betulinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
BetulinicAcidMethylEster
0.5mg
$ 45.00

Iris Biotech GmbH
Betulinic acid methyl ester
10 g
$ 810.00

Iris Biotech GmbH
Betulinic acid methyl ester
1 g
$ 263.25

Iris Biotech GmbH
Betulinic acid methyl ester
5 g
$ 540.00

Iris Biotech GmbH
Betulinic acid methyl ester
2,5 g
$ 398.25

Cayman Chemical
Betulinic Acid methyl ester
5mg
$ 375.00

Cayman Chemical
Betulinic Acid methyl ester
1mg
$ 125.00

Biosynth Carbosynth
Betulinic acid methyl ester
50 mg
$ 137.50

Biosynth Carbosynth
Betulinic acid methyl ester
25 mg
$ 80.00

Arctom
Betulinicacidmethylester
10mg
$ 218.00

Total 14 raw suppliers

Chemical Property of Methyl betulinate

Chemical Property:

Melting Point:222-223°C
Boiling Point:523.5°Cat760mmHg
PKA:15.16±0.70(Predicted)
Flash Point:189.5°C
PSA：46.53000
Density:1.036g/cm³
LogP:7.17790
XLogP3:8.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:470.37599545
Heavy Atom Count:34
Complexity:876

Purity/Quality:

99% ^*data from raw suppliers

BetulinicAcidMethylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=C)C1CCC2(C1C3CCC4C5(CCC(C(C5CCC4(C3(CC2)C)C)(C)C)O)C)C(=O)OC
Isomeric SMILES:CC(=C)[C@@H]1CC[C@]2([C@H]1[C@H]3CC[C@@H]4[C@]5(CC[C@@H](C([C@@H]5CC[C@]4([C@@]3(CC2)C)C)(C)C)O)C)C(=O)OC
Description Betulinic acid methyl ester is a lupane-type triterpenoid and an esterified version of betulinic acid that has been found in Helicteres hirsuta and has diverse biological activities. It inhibits HIV-1 reverse transcriptase (IC50 = 11 μM). Betulinic acid methyl ester is active against L. braziliensis and T. cruzi (IC50s = 69.9 and 93.3 μM, respectively). It induces melanogenesis in (EC50 = 2.5 μM) and inhibits the growth of B16 2F2 melanoma cells in vitro (IC50 = 4.9 μM). Betulinic acid methyl ester is cytotoxic to SK-LU-1, HepG2, HeLa, SK-MEL-2, and AGS cells (IC50s = 60.84, 77.43, 80.17, 66.17, and 69.94 μg/ml, respectively).

Technology Process of Methyl betulinate

There total 31 articles about Methyl betulinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%