Cholesteryl palmitate

Base Information

• Chemical Name: Cholesteryl palmitate
• CAS No.: 601-34-3
• Deprecated CAS: 137036-84-1,870637-59-5
• Molecular Formula: C43H76O2
• Molecular Weight: 625.075
• European Community (EC) Number: 210-002-5
• NSC Number: 59692
• UNII: ZR4D53AD57
• DSSTox Substance ID: DTXSID40889356
• Nikkaji Number: J151.218H
• Wikidata: Q27068156
• Metabolomics Workbench ID: 34671
• Mol file: 601-34-3.mol

Synonyms:cholesteryl palmitate

Chemical Property of Cholesteryl palmitate

Chemical Property:

• Appearance/Colour: white shiny crystalline powder or flakes
• Vapor Pressure: 7.47E-17mmHg at 25°C
• Melting Point: 74-77 °C(lit.)
• Refractive Index: -23.5 ° (C=2, CHCl3)
• Boiling Point: 651.5 °C at 760 mmHg
• Flash Point: 347.8 °C
• PSA: 26.30000
• Density: 0.95 g/cm³
• LogP: 13.42090
• Storage Temp.: −20°C
• Solubility.: Chloroform (Slightly)
• XLogP3: 16.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 21
• Exact Mass: 624.58453166
• Heavy Atom Count: 45
• Complexity: 904

Purity/Quality:

98%,99%, ^*data from raw suppliers

Cholesteryl palmitate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 24/25-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCC(=O)OC1CCC2(C3CCC4(C(C3CC=C2C1)CCC4C(C)CCCC(C)C)C)C
• Isomeric SMILES: CCCCCCCCCCCCCCCC(=O)O[C@H]1CC[C@@]2([C@H]3CC[C@]4([C@H]([C@@H]3CC=C2C1)CC[C@@H]4[C@H](C)CCCC(C)C)C)C
• Uses: Cholesteryl palmitate was used as standard in HPLC analysis of lipids from cooked ground beef and rat liver and mouse muscle tissue samples.

Technology Process of Cholesteryl palmitate

There total 11 articles about Cholesteryl palmitate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

cholesterol (57-88-5) + 1-hexadecylcarboxylic acid (57-10-3) → cholesterol palmitate (601-34-3)

Guidance literature:

With iron(III) chloride hexahydrate; In 1,3,5-trimethyl-benzene; for 24h; Reflux;

DOI:10.1055/s-0028-1083175

Reference yield: 83.0%

cholesterol (57-88-5) + 1-hexadecylcarboxylic acid (57-10-3) → cholesteryl palmitate (601-34-3,137036-84-1)

Guidance literature:

With bromine; triphenylphosphine; for 0.5h; Ambient temperature;

Reference yield:

cholesterol (57-88-5) + n-hexadecanoyl chloride (112-67-4) → cholesterol palmitate (601-34-3)

Guidance literature:

With Amberlyst A-21; In dichloromethane; at 20 ℃;

upstream raw materials:

cholesterol

1-hexadecylcarboxylic acid

glyceroltripalmitate

n-hexadecanoyl chloride

Refernces

• 1、 Komura, Kenichi,Ozaki, Akiyoshi,Ieda, Noboru,Sugi, Yoshihiro. "FeCl3·6H2O as a versatile catalyst for the esterification of steroid alcohols with fatty acids". experimental part. p. 3407 - 3410. Retrieved 2009/05/09.
• 2、 Saroja, M.,Kaimal, T. N. B.. "A CONVENIENT METHOD OF ESTERIFICATION OF FATTY ACIDS. PREPARATION OF ALKYL ESTERS, STEROL ESTERS, WAX ESTERS AND TRIACYLGLYCEROLS". . p. 1423 - 1430. Retrieved 2007/10/02.