Phosphorous acid benzyl ester 2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester methyl ester

Base Information

• Chemical Name: Phosphorous acid benzyl ester 2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester methyl ester
• CAS No.: 1027989-03-2
• Molecular Formula: C₁₄H₂₁O₅P
• Molecular Weight: 300.292
• Mol file: 1027989-03-2.mol

Synonyms:Phosphorous acid benzyl ester 2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester methyl ester

Chemical Property of Phosphorous acid benzyl ester 2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester methyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

Useful:

Technology Process of Phosphorous acid benzyl ester 2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester methyl ester

There total 1 articles about Phosphorous acid benzyl ester 2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl dichlorophosphite (3279-26-3) + (R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol (100-79-8,36543-79-0) + benzyl alcohol (100-51-6,185532-71-2) → Phosphorous acid benzyl ester 2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester methyl ester (1027989-03-2)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; Multistep reaction; 1.) CH₂Cl₂, -78 deg C, 1 h, 2.) CH₂Cl₂, from -78 deg C to 25 deg C, 2 h;

DOI:10.1021/jm960434y

Reference yield:

Phosphorous acid benzyl ester 2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester methyl ester (1027989-03-2) → Phosphoric acid benzyl ester 2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester methyl ester (183999-14-6)

Guidance literature:

With tert.-butylhydroperoxide; In 2,2,4-trimethylpentane; dichloromethane; at 0 - 25 ℃; for 2h; Yield given;

DOI:10.1021/jm960434y

Reference yield:

Phosphorous acid benzyl ester 2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester methyl ester (1027989-03-2) → Phosphoric acid benzyl ester 2,3-dihydroxy-propyl ester methyl ester (183999-15-7)

Guidance literature:

Multi-step reaction with 2 steps

1: t-BuOOH / CH₂Cl₂; 2,2,4-trimethyl-pentane / 2 h / 0 - 25 °C

2: 53 percent / Dowex 50W-X₈ (acid form) / 3.5 h / Ambient temperature

With tert.-butylhydroperoxide; Dowex 50W-X₈ (acid form); In 2,2,4-trimethylpentane; dichloromethane;

DOI:10.1021/jm960434y

upstream raw materials:

methyl dichlorophosphite

(R,S)-2,2-dimethyl-1,3-dioxolane-4-methanol

benzyl alcohol

Downstream raw materials:

Phosphoric acid benzyl ester 2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester methyl ester

Phosphoric acid benzyl ester 2,3-dihydroxy-propyl ester methyl ester

Hexanoic acid 2-(benzyloxy-methoxy-phosphoryloxy)-1-hexanoyloxymethyl-ethyl ester