Ethylene dimethanesulfonate

Base Information

• Chemical Name: Ethylene dimethanesulfonate
• CAS No.: 4672-49-5
• Molecular Formula: C4H10O6S2
• Molecular Weight: 218.252
• European Community (EC) Number: 832-446-4
• NSC Number: 17016
• UNII: EW8V7BJ66Q
• DSSTox Substance ID: DTXSID40196931
• Nikkaji Number: J78.418D
• Wikipedia: Ethane_dimethanesulfonate
• Wikidata: Q27277396
• ChEMBL ID: CHEMBL170630
• Mol file: 4672-49-5.mol

Synonyms:1,2-bis(mesyloxy)ethane;1,2-bis(methanesulfonyloxy)ethane;1,2-ethanediol, 1,2-dimethanesulfonate;1,2-ethanediyl dimethanesulfonate;ethane 1,2-dimethanesulfonate;ethane dimethane sulfonate;ethane dimethanesulfonate;ethane dimethanesulphonate;ethane dimethyl sulfonate;ethylene dimethane sulfonate;ethylene dimethanesulfonate;NSC-10716

Chemical Property of Ethylene dimethanesulfonate

Chemical Property:

• Vapor Pressure: 7.91E-08mmHg at 25°C
• Melting Point: 35-36 °C
• Refractive Index: 1.47
• Boiling Point: 448.914 °C at 760 mmHg
• Flash Point: 225.295 °C
• PSA: 103.50000
• Density: 1.461 g/cm³
• LogP: 1.10040
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Chloroform (Sparingly, Heated), Methanol (Very Slightly)
• XLogP3: -0.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 5
• Exact Mass: 217.99188038
• Heavy Atom Count: 12
• Complexity: 266

Purity/Quality:

99% ^*data from raw suppliers

EthyleneDimethanesulfonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CS(=O)(=O)OCCOS(=O)(=O)C

Technology Process of Ethylene dimethanesulfonate

There total 5 articles about Ethylene dimethanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

ethylene glycol (107-21-1) + methanesulfonyl chloride (124-63-0) → 1,2-bis(methanesulfonyloxy)ethane (4672-49-5)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h;

DOI:10.1021/jm040800a

Reference yield:

methanesulfonic acid (75-75-2,98527-29-8) + ethylene glycol (107-21-1) → 1,2-bis(methanesulfonyloxy)ethane (4672-49-5)

Guidance literature:

With sodium hydroxide; In N,N-dimethyl-formamide; at 90 - 120 ℃; for 4h;

Reference yield:

oxirane (75-21-8,99932-75-9) + methanesulfonyl chloride (124-63-0) → 1,2-bis(methanesulfonyloxy)ethane (4672-49-5)

Guidance literature:

With tetraethylammonium bromide;

upstream raw materials:

ethylene glycol

methanesulfonyl chloride

oxirane

methanesulfonic acid

Downstream raw materials:

2-(α-phenoxy-benzyl)-morpholine hydrochloride

1,4,5-oxadiazepane-4,5-dicarboxylic acid di-tert-butyl ester

9-vinyl-9H-carbazole

N,N'-diphenylethylenediamine

Refernces

• 1、 Ahmad, Randa,Mocaer, Adrien,Gam-Derouich, Sarra,Lamouri, Aazdine,Lecoq, Hélène,Decorse, Philippe,Brunet, Philippe,Mangeney, Claire. "Grafting of polymeric platforms on gold by combining the diazonium salt chemistry and the photoiniferter method". . p. 12 - 20. Retrieved 2015.
• 2、 -. "Phenyl pyrazoline compound with bioactivity and preparation method and application thereof". Paragraph 0059; 0060; 0064. . Retrieved 2019/08/26.
• 3、 -. "PREPARATION OF AMMONIUM OR PHOSPHONIUM BORATE SALTS". Page/Page column 19; 20. . Retrieved 2017/12/27.