C₃₄H₃₂N₂O₈

Base Information

• Chemical Name: C₃₄H₃₂N₂O₈
• CAS No.: 1325206-37-8
• Molecular Formula: C₃₄H₃₂N₂O₈
• Molecular Weight: 596.637
• Mol file: 1325206-37-8.mol

Synonyms:C₃₄H₃₂N₂O₈

Chemical Property of C₃₄H₃₂N₂O₈

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of C₃₄H₃₂N₂O₈

There total 6 articles about C₃₄H₃₂N₂O₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 51.0%

9-(4-(N,N-bis(ethoxycarbonylmethyl)amino)-3-(2-pyridylmethoxy)phenyl)-6-hydroxy-3-oxo-3H-xanthen (1325206-36-7) + methyl iodide (74-88-4) → C34H32N2O8 (1325206-37-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃;

DOI:10.1021/ol201746p

Reference yield:

N,N-(bis(ethoxycarbonylmethyl)amino)-3-(2-pyridylmethoxy)benzaldehyde (1325206-35-6) → C34H32N2O8 (1325206-37-8)

Guidance literature:

Multi-step reaction with 2 steps

1: methanesulfonic acid / 24 h / 80 °C

2: potassium carbonate / N,N-dimethyl-formamide / 60 °C

With methanesulfonic acid; potassium carbonate; In N,N-dimethyl-formamide;

DOI:10.1021/ol201746p

Reference yield:

2-chloromethylpyridine hydrochloride (6959-47-3) → C34H32N2O8 (1325206-37-8)

Guidance literature:

Multi-step reaction with 5 steps

1.1: sodium hydride; potassium iodide / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

1.2: 80 °C / Inert atmosphere

2.1: trifluoroacetic acid / dichloromethane / 20 °C

2.2: Reflux

3.1: trichlorophosphate / 20 °C / Inert atmosphere

4.1: methanesulfonic acid / 24 h / 80 °C

5.1: potassium carbonate / N,N-dimethyl-formamide / 60 °C

With methanesulfonic acid; sodium hydride; potassium carbonate; trifluoroacetic acid; potassium iodide; trichlorophosphate; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ol201746p

upstream raw materials:

[tert-butoxycarbonylmethyl-(2-hydroxy-phenyl)-amino]-acetic acid tert-butyl ester

N,N-bis(tert-butoxycarbonylmethyl)-2-(2-pyridylmethoxy)aniline

9-(4-(N,N-bis(ethoxycarbonylmethyl)amino)-3-(2-pyridylmethoxy)phenyl)-6-hydroxy-3-oxo-3H-xanthen

methyl iodide

Downstream raw materials:

C₃₀H₂₄N₂O₈