N,N-Dipropylbenzamide

Base Information

• Chemical Name: N,N-Dipropylbenzamide
• CAS No.: 14657-86-4
• Molecular Formula: C13H19 N O
• Molecular Weight: 205.3
• Hs Code.: 2924299090
• Mol file: 14657-86-4.mol

Synonyms:Dipropylbenzamide;N,N-Dipropylbenzamide

Chemical Property of N,N-Dipropylbenzamide

Chemical Property:

• Vapor Pressure: 0.000314mmHg at 25°C
• Boiling Point: 320.6°Cat760mmHg
• Flash Point: 138.6°C
• PSA: 20.31000
• Density: 0.974g/cm³
• LogP: 2.94880

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-Dipropylbenzamide

There total 41 articles about N,N-Dipropylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

iodobenzene (591-50-4) + carbon monoxide (201230-82-2) + di-n-propylamine (142-84-7) → N,N-dipropylbenzamide (14657-86-4)

Guidance literature:

With triethylamine; In toluene; at 100 ℃; for 8h; under 3750.38 Torr; Inert atmosphere;

DOI:10.1039/c5ra18692g

Reference yield: 95.0%

benzoyl chloride (98-88-4) + di-n-propylamine (142-84-7) → N,N-dipropylbenzamide (14657-86-4)

Guidance literature:

With pyridine; In tetrahydrofuran; at 20 ℃; for 0.75h;

DOI:10.1021/jo026763h

Reference yield: 93.0%

tri-n-propylamine (102-69-2) + iodobenzene (591-50-4) + carbon monoxide (201230-82-2) → N,N-dipropylbenzamide (14657-86-4)

Guidance literature:

With palladium 10% on activated carbon; oxygen; In acetonitrile; at 100 ℃; for 8h; under 4560.31 Torr; Autoclave; Green chemistry;

DOI:10.1021/acs.joc.5b02385

upstream raw materials:

benzoyl chloride

di-n-propylamine

dibenzoyl disulfide

tri-n-propylamine

Downstream raw materials:

N,N,N'-Tripropyl-benzamidine

(S)-3-(4-nitrophenyl)isobenzofuran-1(3H)-one

diethyl (2-(dipropylcarbamoyl)phenyl)phosphonate

(Difluoro-phenyl-methyl)-dipropyl-amine

Refernces

• 1、 Kolekar, Yuvraj A.,Bhanage, Bhalchandra M.. "Pd-Catalyzed Oxidative Aminocarbonylation of Arylboronic Acids with Unreactive Tertiary Amines via C-N Bond Activation". . p. 14028 - 14035. Retrieved 2021/05/29.
• 2、 Li, Hongji,Liu, Meijiang,Liu, Huifang,Luo, Nengchao,Zhang, Chaofeng,Wang, Feng. "Amine-Mediated Bond Cleavage in Oxidized Lignin Models". . p. 4660 - 4665. Retrieved 2020/07/04.