C-{[4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]phenyl]amino}-N-[N-{(9S,12S)-7,10-dioxo-9-isopropyl-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-14,16,17-trien-12-ylcarbonyl}glycyl]-(S)-isoleucine benzyl ester

Base Information

Chemical Name:C-{[4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]phenyl]amino}-N-[N-{(9S,12S)-7,10-dioxo-9-isopropyl-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-14,16,17-trien-12-ylcarbonyl}glycyl]-(S)-isoleucine benzyl ester
CAS No.:623562-59-4
Molecular Formula:C₄₈H₆₆N₆O₁₀
Molecular Weight:887.086
Hs Code.:

C-{[4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]phenyl]amino}-N-[N-{(9S,12S)-7,10-dioxo-9-isopropyl-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-14,16,17-trien-12-ylcarbonyl}glycyl]-(S)-isoleucine benzyl ester

Synonyms:C-{[4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]phenyl]amino}-N-[N-{(9S,12S)-7,10-dioxo-9-isopropyl-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-14,16,17-trien-12-ylcarbonyl}glycyl]-(S)-isoleucine benzyl ester

Suppliers and Price of C-{[4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]phenyl]amino}-N-[N-{(9S,12S)-7,10-dioxo-9-isopropyl-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-14,16,17-trien-12-ylcarbonyl}glycyl]-(S)-isoleucine benzyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of C-{[4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]phenyl]amino}-N-[N-{(9S,12S)-7,10-dioxo-9-isopropyl-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-14,16,17-trien-12-ylcarbonyl}glycyl]-(S)-isoleucine benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of C-{[4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]phenyl]amino}-N-[N-{(9S,12S)-7,10-dioxo-9-isopropyl-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-14,16,17-trien-12-ylcarbonyl}glycyl]-(S)-isoleucine benzyl ester

There total 5 articles about C-{[4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]phenyl]amino}-N-[N-{(9S,12S)-7,10-dioxo-9-isopropyl-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-14,16,17-trien-12-ylcarbonyl}glycyl]-(S)-isoleucine benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 58885-58-8
N-tert-butoxycarbonyl-3-aminopropanol

: 623562-59-4
C-{[4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]phenyl]amino}-N-[N-{(9S,12S)-7,10-dioxo-9-isopropyl-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-14,16,17-trien-12-ylcarbonyl}glycyl]-(S)-isoleucine benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / PPh₃; DEAD / tetrahydrofuran / 20 °C

2: 89 percent / H₂ / 10 percent Pd/C / methanol / 6 h

3: 60 mg / Et₃N / CH₂Cl₂ / 48 h / Heating

With hydrogen; triethylamine; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1039/b211644h

Reference yield:

: 100-02-7,78813-13-5,89830-32-0
4-nitro-phenol

: 623562-59-4
C-{[4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]phenyl]amino}-N-[N-{(9S,12S)-7,10-dioxo-9-isopropyl-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-14,16,17-trien-12-ylcarbonyl}glycyl]-(S)-isoleucine benzyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / PPh₃; DEAD / tetrahydrofuran / 20 °C

2: 89 percent / H₂ / 10 percent Pd/C / methanol / 6 h

3: 60 mg / Et₃N / CH₂Cl₂ / 48 h / Heating

With hydrogen; triethylamine; triphenylphosphine; diethylazodicarboxylate; palladium on activated charcoal; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1039/b211644h

Reference yield:

: 623562-63-0
[3-(4-nitro-phenoxy)-propyl]-carbamic acid tert-butyl ester

: 623562-59-4
C-{[4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]phenyl]amino}-N-[N-{(9S,12S)-7,10-dioxo-9-isopropyl-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-14,16,17-trien-12-ylcarbonyl}glycyl]-(S)-isoleucine benzyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 89 percent / H₂ / 10 percent Pd/C / methanol / 6 h

2: 60 mg / Et₃N / CH₂Cl₂ / 48 h / Heating

With hydrogen; triethylamine; palladium on activated charcoal; In methanol; dichloromethane;
DOI:10.1039/b211644h