623562-63-0

Basic information

• Product Name: [3-(4-nitro-phenoxy)-propyl]-carbamic acid tert-butyl ester
• Synonyms: [3-(4-nitro-phenoxy)-propyl]-carbamic acid tert-butyl ester
• CAS NO: 623562-63-0
• Molecular Weight: 296.323
• Mol File: 623562-63-0.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: [3-(4-nitro-phenoxy)-propyl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [3-(4-nitro-phenoxy)-propyl]-carbamic acid tert-butyl ester(623562-63-0)
• EPA Substance Registry System: [3-(4-nitro-phenoxy)-propyl]-carbamic acid tert-butyl ester(623562-63-0)

Safety Data

• Hazardous Substances Data: 623562-63-0(Hazardous Substances Data)

Usage

General Description

The chemical compound [3-(4-nitro-phenoxy)-propyl]-carbamic acid tert-butyl ester is a type of carbamate ester. It is composed of a carbamic acid group, a tert-butyl ester group, and a 3-(4-nitro-phenoxy)-propyl group. The 4-nitro-phenoxy group is known for its nitro functional group, which contains a nitrogen atom bonded to three oxygen atoms and is commonly used in the production of dyes and pesticides. The carbamic acid group is a functional group containing a carbonyl group attached to an amino group. [3-(4-nitro-phenoxy)-propyl]-carbamic acid tert-butyl ester is often used in the synthesis of pharmaceuticals and agrochemicals. It is important to handle this chemical compound with care and follow proper safety precautions due to its potential health hazards.

Upstream product

• 100-02-7 4-nitro-phenol 
• 58885-58-8 N-tert-butoxycarbonyl-3-aminopropanol 
• 118119-47-4 di-tert-butyl dicarbonate 
• 100841-04-1 3-(4-nitrophenoxy)propan-1-amine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 83948-53-2 3-bromopropylamine tert-butylcarbamate 
• 350-46-9 4-Fluoronitrobenzene 

Downstream Products

• 627463-31-4 ethyl-[3-(4-nitrophenoxy)propyl]carbamic acid tert-butyl ester 
• 22404-14-4 C₁₁H₁₄N₂O₄ 
• 100841-04-1 3-(4-nitrophenoxy)propan-1-amine 
• 66971-02-6 3-(4-nitrophenoxy)-1-propanol 
• 623562-59-4 C-{[4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]phenyl]amino}-N-[N-{(9S,12S)-7,10-dioxo-9-isopropyl-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-14,16,17-trien-12-ylcarbonyl}glycyl]-(S)-isoleucine benzyl ester 
• 623562-57-2 C-{[4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]phenyl]amino}-N-[N-{(9S,12S)-7,10-dioxo-9-isopropyl-2-oxa-8,11-diazabicyclo[12.2.2]octadeca-14,16,17-trien-12-ylcarbonyl}glycyl]-(S)-isoleucine 
• 623562-56-1 1-amino-4-[3-[N-(tert-butoxycarbonyl)amino]propan-1-yloxy]benzene 
• 1448718-88-4 (S)-N-[4-[3-[[3-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxo-2,5-dihydro-pyrrol-1-yl)-propionylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]-1-oxopropyl]amino]propoxy]-phenyl]-3-[2-[3-[guanidino]-benzoylamino]-acetylamino]-succinamic acid 
• 1448718-87-3 (S)-N-[4-(3-amino-propoxy)-phenyl]-3-(2-(3-(guanidino)-benzoylamino)-acetylamino)-succinamic acid trifluoroacetate 

Relevant articles and documents

Functionalized azobenzene platinum(II) complexes as putative anticancer compounds

The synthesis and characterization of four platinum(II) complexes using azobenzenes conveniently functionalized as ligands has been carried out. The characteristic photochemical behavior of the complexes due to the presence of azobenzene-type ligands and the role of the ligands in the activation of the complexes has been studied. Their promising cytotoxicity observed in HeLa cells prompted us to study the mechanism of action of these complexes as cytostatic agents. The interaction of the compounds with DNA, studied by circular dichroism, revealed a differential activity of the Pt(II) complexes upon irradiation. The intercalation abilities of the complexes as well as their reactivity with common proteins present in the blood stream allows to confirm some of the compounds obtained as good anticancer candidates.

heteroaromatic macrocyclic derivatives as protein kinase inhibitors

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MACROCYCLES AS KINASE INHIBITORS

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