(E)-1-(o-tolyl)ethanone O-methyl oxime

Base Information

• Chemical Name: (E)-1-(o-tolyl)ethanone O-methyl oxime
• CAS No.: 136534-18-4
• Molecular Formula: C₁₀H₁₃NO
• Molecular Weight: 163.219
• Mol file: 136534-18-4.mol

Synonyms:(E)-1-(o-tolyl)ethanone O-methyl oxime

Chemical Property of (E)-1-(o-tolyl)ethanone O-methyl oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-1-(o-tolyl)ethanone O-methyl oxime

There total 5 articles about (E)-1-(o-tolyl)ethanone O-methyl oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

(E)-acetophenone O-methyloxime (15754-20-8) + potassium trifluoro(methyl)boranuide → (E)-1-(o-tolyl)ethanone O-methyl oxime (136534-18-4)

Guidance literature:

With dipotassium hydrogenphosphate; potassium dihydrogenphosphate; palladium diacetate; acetic acid; at 60 ℃; for 12h; Reagent/catalyst; Temperature; Catalytic behavior; Electrolysis;

DOI:10.1039/c7cc07429h

Reference yield: 72.0%

N-methoxylamine hydrochloride (593-56-6) + 2-Methylacetophenone (577-16-2,122382-54-1) → (E)-1-(o-tolyl)ethanone O-methyl oxime (136534-18-4)

Guidance literature:

With sodium acetate; In ethanol; water; at 70 ℃; for 2h;

DOI:10.1002/adsc.201200401

Reference yield:

acetophenone (98-86-2) → (E)-1-(o-tolyl)ethanone O-methyl oxime (136534-18-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium acetate / water; ethanol / 2 h / Reflux

2: palladium diacetate; dipotassium hydrogenphosphate; potassium dihydrogenphosphate; acetic acid / 12 h / 60 °C / Electrolysis

With dipotassium hydrogenphosphate; potassium dihydrogenphosphate; sodium acetate; palladium diacetate; acetic acid; In ethanol; water;

DOI:10.1039/c7cc07429h

upstream raw materials:

N-methoxylamine hydrochloride

2-Methylacetophenone

(E)-acetophenone O-methyloxime

acetophenone

Downstream raw materials:

(E)-(2-(1-(methoxyimino)ethyl)-3-methylphenyl)(phenyl)methanone

(E)-1-(6-methyl-2-nitrophenyl)ethanone O-methyl oxime