4-Phenylquinazolin-2-amine

Base Information

Chemical Name:4-Phenylquinazolin-2-amine
CAS No.:14005-50-6
Molecular Formula:C14H11 N3
Molecular Weight:221.261
Hs Code.:
NSC Number:107148
DSSTox Substance ID:DTXSID60296023
Nikkaji Number:J1.575.313G,J2.331.476B
Wikidata:Q82036325
Pharos Ligand ID:15YA8QYLSW5M
ChEMBL ID:CHEMBL4791612
Mol file:14005-50-6.mol

Synonyms:4-phenylquinazolin-2-amine;14005-50-6;2-amino-4-phenylquinazoline;2-Quinazolinamine, 4-phenyl-;CHEMBL4791612;NSC 107148;NSC107148;4-Phenyl-2-quinazolinamine;SCHEMBL421987;4-Phenylquinazoline-2-ylnitrogen;DTXSID60296023;BDBM50548112;AKOS015943125;NSC-107148;CS-0116681

Suppliers and Price of 4-Phenylquinazolin-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 7 raw suppliers

Chemical Property of 4-Phenylquinazolin-2-amine

Chemical Property:

Vapor Pressure:3.24E-08mmHg at 25°C
Boiling Point:447.9°C at 760 mmHg
Flash Point:255.1°C
Density:1.246g/cm³
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:221.095297364
Heavy Atom Count:17
Complexity:250

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NC(=NC3=CC=CC=C32)N

Technology Process of 4-Phenylquinazolin-2-amine

There total 5 articles about 4-Phenylquinazolin-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 420-04-2
CYANAMID

: 2835-77-0
(2-aminophenyl)(phenyl)methanone

: 14005-50-6
2-amino-4-phenyl-2(1H)-quinazoline

Guidance literature:: With toluene-4-sulfonic acid; In N,N-dimethyl-formamide; at 110 ℃; for 12h; Solvent; Reagent/catalyst; Temperature;
DOI:10.1016/j.tetlet.2017.02.033

Reference yield: 60.0%

: 23441-75-0
4-phenyl-1H-quinazolin-2-one

: 14005-50-6
2-amino-4-phenyl-2(1H)-quinazoline

Guidance literature:: With phosphorodiimidate; In diphenylether; at 250 ℃; for 3h;
DOI:10.3987/R-1986-11-3075

Reference yield: 45.0%

: 13047-06-8
o-bromobenzophenone

: 50-01-1
guanidine hydrochloride

: 14005-50-6
2-amino-4-phenyl-2(1H)-quinazoline

Guidance literature:: o-bromobenzophenone; guanidine hydrochloride; With caesium carbonate; L-proline; In N,N-dimethyl-formamide; for 0.333333h; Inert atmosphere;

With copper(l) iodide; caesium carbonate; In N,N-dimethyl-formamide; at 120 ℃; for 40h; Inert atmosphere;
DOI:10.1055/s-0029-1216871