3-bromo-2-hydroxy-5-methylbenzeneacetic acid

Base Information

• Chemical Name: 3-bromo-2-hydroxy-5-methylbenzeneacetic acid
• CAS No.: 96625-84-2
• Molecular Formula: C₉H₉BrO₃
• Molecular Weight: 245.073
• Mol file: 96625-84-2.mol

Synonyms:3-bromo-2-hydroxy-5-methylbenzeneacetic acid

Chemical Property of 3-bromo-2-hydroxy-5-methylbenzeneacetic acid

Chemical Property:

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-bromo-2-hydroxy-5-methylbenzeneacetic acid

There total 4 articles about 3-bromo-2-hydroxy-5-methylbenzeneacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

2-(2-hydroxy-5-methylphenyl)acetic acid (41873-66-9) → 3-bromo-2-hydroxy-5-methylbenzeneacetic acid (96625-84-2)

Guidance literature:

With N-Bromosuccinimide; In N,N-dimethyl-formamide; for 18h; Ambient temperature;

DOI:10.1021/jo00376a013

Reference yield:

p-methylanizole (104-93-8) → 3-bromo-2-hydroxy-5-methylbenzeneacetic acid (96625-84-2)

Guidance literature:

Multi-step reaction with 3 steps

3: 88 percent / N-bromosuccinimide / dimethylformamide

With N-Bromosuccinimide; In N,N-dimethyl-formamide;

DOI:10.1039/c39840001660

Reference yield:

5-methyl-2-hydroxyacetophenone (1450-72-2) → 3-bromo-2-hydroxy-5-methylbenzeneacetic acid (96625-84-2)

Guidance literature:

Multi-step reaction with 2 steps

2: 88 percent / N-bromosuccinimide / dimethylformamide

With N-Bromosuccinimide; In N,N-dimethyl-formamide;

DOI:10.1039/c39840001660

upstream raw materials:

formaldehyd

2-bromo-p-cresol

dimethyl amine

2-(2-hydroxy-5-methylphenyl)acetic acid

Downstream raw materials:

N,N-bis(phenylmethyl)-3,3''-dibromo-2,2',2''-trimethoxy-5,5''-dimethyl-1,1':3',1''-terphenyl-5'-amine

2,4-Bis-(3-bromo-2-methoxy-5-methyl-phenyl)-3-oxo-butyric acid ethyl ester

ethyl 3-bromo-2-methoxy-5-methylbenzeneacetate

1,3-bis(3-bromo-2-methoxy-5-methylphenyl)-2-propanone