(2S)-2-[(t-butoxycarbonyl)amino]-3-[4-(4-nitrophenoxy)phenyl]propanoic acid methyl ester

Base Information

Chemical Name:(2S)-2-[(t-butoxycarbonyl)amino]-3-[4-(4-nitrophenoxy)phenyl]propanoic acid methyl ester
CAS No.:914639-64-8
Molecular Formula:C₂₁H₂₄N₂O₇
Molecular Weight:416.431
Hs Code.:

Synonyms:(2S)-2-[(t-butoxycarbonyl)amino]-3-[4-(4-nitrophenoxy)phenyl]propanoic acid methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2S)-2-[(t-butoxycarbonyl)amino]-3-[4-(4-nitrophenoxy)phenyl]propanoic acid methyl ester

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Technology Process of (2S)-2-[(t-butoxycarbonyl)amino]-3-[4-(4-nitrophenoxy)phenyl]propanoic acid methyl ester

There total 6 articles about (2S)-2-[(t-butoxycarbonyl)amino]-3-[4-(4-nitrophenoxy)phenyl]propanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.2%

: 914639-63-7
(S)-2-((tert-butoxycarbonyl)amino)-3-(4-(4-nitrophenoxy)phenyl)propanoic acid

: 74-88-4
methyl iodide

: 914639-64-8
(2S)-2-[(t-butoxycarbonyl)amino]-3-[4-(4-nitrophenoxy)phenyl]propanoic acid methyl ester

Guidance literature:: With sodium hydrogencarbonate; In N,N-dimethyl-formamide; at 20 ℃; for 6h;

Reference yield: 58.0%

: 4326-36-7
(S)-N-(tert-butoxycarbonyl)tyrosine methyl ester

: 586-78-7
para-nitrophenyl bromide

: 914639-64-8
(2S)-2-[(t-butoxycarbonyl)amino]-3-[4-(4-nitrophenoxy)phenyl]propanoic acid methyl ester

Guidance literature:: With copper(l) iodide; caesium carbonate; N,N`-dimethylethylenediamine; In toluene; at 100 ℃; for 24h; Schlenk technique; Sealed tube;
DOI:10.1007/s00726-012-1337-4