α carbomethoxy β methyl stilbene cis

Base Information

• Chemical Name: α carbomethoxy β methyl stilbene cis
• CAS No.: 42443-38-9
• Molecular Formula: C₁₇H₁₆O₂
• Molecular Weight: 252.313
• Mol file: 42443-38-9.mol

Synonyms:α carbomethoxy β methyl stilbene cis

Chemical Property of α carbomethoxy β methyl stilbene cis

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of α carbomethoxy β methyl stilbene cis

There total 20 articles about α carbomethoxy β methyl stilbene cis which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

C18H18O5S + phenylboronic acid (98-80-6) → α carbomethoxy β methyl stilbene cis (42443-38-9)

Guidance literature:

With dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; palladium diacetate; N-ethyl-N,N-diisopropylamine; In water; toluene; at 80 - 85 ℃; for 2h; Inert atmosphere;

DOI:10.1002/chem.201405150

Reference yield: 96.0%

(Z)-methyl 2-phenyl-3-(diphenoxyphosphoryloxy)but-2-enoate + phenylmagnesium bromide (100-58-3) → α carbomethoxy β methyl stilbene cis (42443-38-9)

Guidance literature:

phenylmagnesium bromide; With zinc(II) chloride; In tetrahydrofuran; acetonitrile; at 0 - 5 ℃; for 0.5h; Inert atmosphere;

(Z)-methyl 2-phenyl-3-(diphenoxyphosphoryloxy)but-2-enoate; With [1,4-bis(diphenylphosphino)butane] palladium(ll) dichloride; In tetrahydrofuran; acetonitrile; at 0 - 65 ℃; for 2h; Inert atmosphere;

DOI:10.1039/c5ob01097g

Reference yield: 63.0%

methyl 2-oxo-2-phenylacetate (15206-55-0) + (1-bromoethyl)benzne (585-71-7,38661-81-3) → (E)-,(Z)-methyl-2,3-diphenyl-2-butenoate (42443-37-8,42443-38-9)

Guidance literature:

With Hexamethylphosphorous triamide; In water; acetonitrile; at -40 - 60 ℃; for 3.5h;

DOI:10.1021/acs.orglett.0c00620

upstream raw materials:

iodobenzene

methyllithium

phenylpropynoic acid methyl ester

methanol

Downstream raw materials:

2,3-diphenyl-crotonic acid