ACETYLACETICACID,SODIUMSALT

Base Information

• Chemical Name: ACETYLACETICACID,SODIUMSALT
• CAS No.: 623-58-5
• Molecular Formula: C4H6 O3 . Na
• Molecular Weight: 124.072
• Hs Code.: 2918300090
• Mol file: 623-58-5.mol

Synonyms:Acetoaceticacid, sodium salt (8CI); Butanoic acid, 3-oxo-, sodium salt (9CI); Sodiumacetoacetate

Chemical Property of ACETYLACETICACID,SODIUMSALT

Chemical Property:

• Vapor Pressure: 0.015mmHg at 25°C
• Boiling Point: 237.7°C at 760 mmHg
• Flash Point: 111.8°C
• PSA: 57.20000
• LogP: -1.28460

Purity/Quality:

97% ^*data from raw suppliers

Acetoaceticacidsodiumsalt >98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Sodium Acetoacetate is an intermediate used in the synthesis of 1-Piperidin-2-ylacetone (B449983(M)). Sodium Acetoacetate could be useful in the asymmetric synthesis of pelletierine via organocatalytic Mannich and intramolemolecular aza-Michael reactions

Technology Process of ACETYLACETICACID,SODIUMSALT

There total 3 articles about ACETYLACETICACID,SODIUMSALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium (7440-23-5) + ethyl acetate (141-78-6) → sodium acetate (127-09-3) + sodium aceto-acetate (623-58-5)

Guidance literature:

treating ethylacetate with Na;;

DOI:10.1039/JR9280000591

Reference yield:

sodium cyanide (773837-37-9) + acetonedicarboxylic acid (542-05-2) → C6H5NO5(2-)*2Na(1+) + C5H6NO3(1-)*Na(1+) + Natrium-3-ketoglutarat (22004-94-0) + sodium aceto-acetate (623-58-5) + acetone (67-64-1)

Guidance literature:

With water; sodium hydroxide; at 0 - 20 ℃; for 216h; pH=12.5;

DOI:10.1002/chem.201701497

Reference yield:

sodium cyanide (773837-37-9) + acetonedicarboxylic acid (542-05-2) → C6H5NO5(2-)*2Na(1+) + C5H6NO3(1-)*Na(1+) + C6H7NO6(2-)*2Na(1+) + Natrium-3-ketoglutarat (22004-94-0) + sodium aceto-acetate (623-58-5) + acetone (67-64-1)

Guidance literature:

With water; sodium hydroxide; at 0 - 20 ℃; for 192h; pH=8;

DOI:10.1002/chem.201701497

upstream raw materials:

sodium

ethyl acetate

sodium cyanide

acetonedicarboxylic acid

Downstream raw materials:

2-dimethylaminomethyl-1-buten-3-one

4-diethylamino-3-(diethylamino-methyl)-butan-2-one

1-(2'-cyclohexenyl)-2-propanone

β-hydroxybutyric acid